{"id":"W3200767835","doi":"10.1080/15548627.2021.1965711","title":"Global Proximity Interactome of the Human Macroautophagy Pathway","year":2021,"lang":"hu","type":"article","venue":"Autophagy","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; Dalhousie University; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Interactome; Biology; Gene ontology; Computational biology; Identification (biology); Ontology; Protein–protein interaction; Cell biology; Gene; Plasma protein binding; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001754088,0.0002975424,0.0003422893,0.00001895291,0.0001679336,0.00004068391,0.0004437781,0.0003851526,0.0005221525],"category_scores_gemma":[0.00005058982,0.0002552335,0.0005048798,0.0002934244,0.0002312247,0.000009672149,0.0002812207,0.0001968848,0.00001654405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005340067,"about_ca_system_score_gemma":0.0004134804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009036999,"about_ca_topic_score_gemma":0.000339894,"domain_scores_codex":[0.9980169,0.0001886394,0.0005401326,0.0005787557,0.0002908262,0.0003847738],"domain_scores_gemma":[0.9984532,0.000008596165,0.0002538804,0.0009420567,0.0002378938,0.0001044007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003504373,0.0003311099,0.01185348,0.0001517155,0.0001639886,0.00006814743,0.0001463119,0.00001516641,0.9817353,0.003025795,0.0001034684,0.002370495],"study_design_scores_gemma":[0.0007733849,0.0001348254,0.09824266,0.00007640843,0.00008806611,0.00006316369,0.00007324455,0.00004792838,0.845391,0.0005155092,0.05432467,0.0002691657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864333,0.00535673,0.001063968,0.0002098263,0.001088587,0.0002507925,0.0002423374,0.00001468142,0.005339765],"genre_scores_gemma":[0.9932042,0.0001571461,0.00007713251,0.0002490158,0.0002813265,0.000008546131,0.001440944,0.0000263998,0.004555282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1363443,"threshold_uncertainty_score":0.99999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009093312538262982,"score_gpt":0.242077692695602,"score_spread":0.232984380157339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}