{"id":"W3200767835","doi":"10.1080/15548627.2021.1965711","title":"Global Proximity Interactome of the Human Macroautophagy Pathway","year":2021,"lang":"hu","type":"article","venue":"Autophagy","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; Dalhousie University; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Interactome; Biology; Gene ontology; Computational biology; Identification (biology); Ontology; Protein–protein interaction; Cell biology; Gene; Plasma protein binding; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006121504,0.0002726772,0.0002959678,0.001433536,0.0004202991,0.0004070998,0.00007924785,0.0002154835,0.004370158],"category_scores_gemma":[0.0001501744,0.00008457779,0.000286247,0.001436357,0.00009930166,0.0002216635,0.0004319513,0.0001753014,0.0008056429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002563726,"about_ca_system_score_gemma":0.0002491779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001923868,"about_ca_topic_score_gemma":0.003454093,"domain_scores_codex":[0.9998986,0.000007941452,0.000006488811,0.00004160393,0.00002493596,0.00002050362],"domain_scores_gemma":[0.9998764,0.0000290635,0.00003682144,0.000009727183,0.00001642266,0.00003156179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003108577,0.00009135787,0.07677691,0.001347846,0.0005158453,0.0005902618,0.0002514486,0.00150343,0.8805011,0.001989854,0.003863394,0.02945995],"study_design_scores_gemma":[0.00007848448,0.0002869149,0.8294367,0.00007693805,0.000480229,0.002272593,0.0004379626,0.004988233,0.1343391,0.001400684,0.0261583,0.00004386524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9614876,0.00377886,0.001518252,0.0000903893,0.00001342741,0.0000174131,0.02932294,0.0002343503,0.003536734],"genre_scores_gemma":[0.9475824,0.00146692,0.003107638,0.00006565182,0.00001987131,0.00008127501,0.04286719,0.00004309605,0.004765874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004370158,"threshold_uncertainty_score":0.01461959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009093312538262982,"score_gpt":0.242077692695602,"score_spread":0.232984380157339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}