{"id":"W3200813633","doi":"10.3389/fphys.2021.739001","title":"A C-Terminally Truncated Variant of Neurospora crassa VDAC Assembles Into a Partially Functional Form in the Mitochondrial Outer Membrane and Forms Multimers in vitro","year":2021,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Voltage-dependent anion channel; Bacterial outer membrane; Porin; Neurospora crassa; Translocase of the outer membrane; Biology; Biochemistry; Mitochondrion; Biophysics; Cell biology; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001780067,0.0005025012,0.0003053003,0.00019691,0.0001980539,0.0003386508,0.0003021752,0.0002266063,0.0006013606],"category_scores_gemma":[0.0002192471,0.0001800927,0.0003791588,0.0002927796,0.0002364399,0.0001651094,0.0002129054,0.0005702584,0.0005113035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006990524,"about_ca_system_score_gemma":0.0003822267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003709751,"about_ca_topic_score_gemma":0.00316606,"domain_scores_codex":[0.9997835,0.00002663531,0.00003455508,0.00005545427,0.00006430656,0.00003559585],"domain_scores_gemma":[0.9997579,0.00003168229,0.00005013978,0.00005893572,0.00004073056,0.00006046392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005540058,0.0000175453,0.0001827934,0.0000219132,0.000007376761,0.0000401416,0.00001429162,0.00003689542,0.9991508,0.00004294745,0.00002375754,0.0004062491],"study_design_scores_gemma":[0.00001727329,0.0001597486,0.005829087,0.000006993199,0.0000284914,0.00041305,0.00004813334,0.001314127,0.9879121,0.00003412716,0.004223857,0.00001291415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955716,0.0009360362,0.001922022,0.00006660286,0.00003579132,0.00002727426,0.0006948396,0.00006722812,0.0006786087],"genre_scores_gemma":[0.9891911,0.0005937251,0.00327315,0.00005936733,0.00001181546,0.00002612545,0.003675512,0.00005605182,0.003113172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003709751,"threshold_uncertainty_score":0.007376313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008929157015505004,"score_gpt":0.2274955336237855,"score_spread":0.2185663766082805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}