{"id":"W3201023713","doi":"10.1128/mbio.01763-21","title":"Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions","year":2021,"lang":"en","type":"article","venue":"mBio","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Guelph","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Nottingham; National Science Foundation; Canadian Institutes of Health Research; National Institute of General Medical Sciences; National Institute for Health and Care Research; Government of Canada; Cystic Fibrosis Trust; Cystic Fibrosis Foundation; Paul G. Allen Family Foundation; UK Research and Innovation","keywords":"Cystic fibrosis; Intensive care medicine; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001944982,0.0001304071,0.0002217777,0.0001303561,0.0002121953,0.000087493,0.00006679162,0.00003027729,0.00001133555],"category_scores_gemma":[0.0001729218,0.00009706288,0.00004138563,0.0005507595,0.00004318982,0.0001044585,0.0001425511,0.0003063959,0.00001091441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002313024,"about_ca_system_score_gemma":0.0001869421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328003,"about_ca_topic_score_gemma":0.0006025403,"domain_scores_codex":[0.9988521,0.0001104859,0.0002129996,0.0003275346,0.0002161976,0.0002806284],"domain_scores_gemma":[0.9993634,0.00009706281,0.00002491283,0.0003237822,0.00006042163,0.0001304859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001128796,0.01394015,0.1980722,0.003661484,0.001186333,0.0002637274,0.05589513,0.06486601,0.1686691,0.002611078,0.004574202,0.4851318],"study_design_scores_gemma":[0.01876991,0.006194168,0.4392883,0.005241119,0.001280197,0.001813872,0.08348095,0.1608424,0.01864988,0.0003715111,0.2616245,0.002443271],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708319,0.02515281,0.0009178958,0.001126657,0.0006518172,0.001138203,0.00002889333,0.00006360826,0.0000882159],"genre_scores_gemma":[0.9974045,0.0004619661,0.000364812,0.00001014766,0.0004958904,0.001081424,0.00001030322,0.00001873204,0.0001522726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4826885,"threshold_uncertainty_score":0.3958109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08826486137067804,"score_gpt":0.3224702720866676,"score_spread":0.2342054107159895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}