{"id":"W3201023740","doi":"10.1002/iid3.530","title":"Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice","year":2021,"lang":"en","type":"article","venue":"Immunity Inflammation and Disease","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Institute of Infection and Immunity; Canadian Institutes of Health Research; University of Ottawa","funders":"King Saud bin Abdulaziz University for Health Science; Canadian Institutes of Health Research; University of Ottawa","keywords":"CD8; Splenocyte; Cytokine; T cell; Flow cytometry; Cell growth; Peripheral blood mononuclear cell; Interleukin-7 receptor; In vivo; Biology; Immunology; Receptor; Spleen; Interleukin 15; Interleukin 2; Cell biology; IL-2 receptor; Interleukin; Internal medicine; Medicine; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003771398,0.001016146,0.0005811556,0.001013147,0.0001946087,0.0003782165,0.0002549627,0.0007147922,0.002024865],"category_scores_gemma":[0.0001933372,0.0002603738,0.0003631126,0.0002203938,0.0003855478,0.0003991277,0.0002381056,0.00152829,0.0007819359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002506757,"about_ca_system_score_gemma":0.0003529574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002977123,"about_ca_topic_score_gemma":0.0004222697,"domain_scores_codex":[0.9995331,0.00007491755,0.00003151151,0.00009080079,0.0001285687,0.0001411931],"domain_scores_gemma":[0.9995671,0.0000735846,0.0001070603,0.00004296703,0.00004312964,0.0001661775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001026307,0.0006008926,0.0001524434,0.00005409008,0.000008344079,0.00005103517,0.00002407973,0.000157874,0.9952374,0.00008253765,0.00008966822,0.002515471],"study_design_scores_gemma":[0.000184029,0.007337418,0.001931014,0.0000177719,0.00003395016,0.0001802018,0.00002583725,0.001411752,0.9873943,0.0000823634,0.001392954,0.000008493822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989405,0.00185885,0.003413266,0.0002014201,0.0001490417,0.0001790108,0.0008003677,0.0003560553,0.003636958],"genre_scores_gemma":[0.9865155,0.001084182,0.003454438,0.0001496352,0.000112078,0.0002435679,0.001131667,0.00007302647,0.007235822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002024865,"threshold_uncertainty_score":0.006773829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120259805058155,"score_gpt":0.2476786057913242,"score_spread":0.2356526252855087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}