{"id":"W3201023740","doi":"10.1002/iid3.530","title":"Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice","year":2021,"lang":"en","type":"article","venue":"Immunity Inflammation and Disease","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Institute of Infection and Immunity; Canadian Institutes of Health Research; University of Ottawa","funders":"King Saud bin Abdulaziz University for Health Science; Canadian Institutes of Health Research; University of Ottawa","keywords":"CD8; Splenocyte; Cytokine; T cell; Flow cytometry; Cell growth; Peripheral blood mononuclear cell; Interleukin-7 receptor; In vivo; Biology; Immunology; Receptor; Spleen; Interleukin 15; Interleukin 2; Cell biology; IL-2 receptor; Interleukin; Internal medicine; Medicine; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002147684,0.0001202023,0.0001620151,0.000179007,0.0001557504,0.00003677196,0.00006134635,0.0001119432,0.001611995],"category_scores_gemma":[0.0002837014,0.0001314396,0.00004900155,0.0002005845,0.00005689135,0.0003918406,0.00006865088,0.0003305905,0.0001643567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007156516,"about_ca_system_score_gemma":0.000158865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006066008,"about_ca_topic_score_gemma":0.0004112024,"domain_scores_codex":[0.9988874,0.0004173625,0.0002689916,0.0001812563,0.00003099689,0.00021405],"domain_scores_gemma":[0.9994928,0.00009351297,0.00008677137,0.0002038448,0.00007415321,0.00004893213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002533812,0.0005520253,0.01369665,0.0001163873,0.00003479325,0.00002946892,0.0007555169,0.00006167299,0.9724151,0.0007633312,0.002379048,0.00666221],"study_design_scores_gemma":[0.009474558,0.0002046879,0.402474,0.000242693,0.00005706526,0.00005397131,0.003513418,0.0008063143,0.4749379,0.00103591,0.1064951,0.0007043029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940501,0.001410823,0.00005338761,0.001683292,0.001027642,0.0001498411,0.000007303861,0.0000409643,0.001576651],"genre_scores_gemma":[0.9953884,0.0003806784,0.00000882697,0.0003134198,0.00001374078,0.00002173925,0.000154807,0.000007411995,0.003710926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4974771,"threshold_uncertainty_score":0.9993007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120259805058155,"score_gpt":0.2476786057913242,"score_spread":0.2356526252855087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}