{"id":"W3201098337","doi":"10.1016/j.joca.2021.06.014","title":"Voluntary running attenuates behavioural signs of low back pain: dimorphic regulation of intervertebral disc inflammation in male and female SPARC-null mice","year":2021,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research; Louise and Alan Edwards Foundation","keywords":"CXCL1; Inflammation; Medicine; Downregulation and upregulation; CXC chemokine receptors; Internal medicine; Immunology; Endocrinology; Psychology; Chemokine; Biology; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002110851,0.000126343,0.0003770912,0.00009224861,0.00002532328,0.00001285733,0.00003282984,0.00009410092,0.0004214387],"category_scores_gemma":[0.00006317814,0.0001249962,0.00007851041,0.0001275852,0.000133285,0.0001987047,0.00007337424,0.0001083741,0.000004160523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001409893,"about_ca_system_score_gemma":0.00002407199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008469017,"about_ca_topic_score_gemma":0.0008781154,"domain_scores_codex":[0.9989374,0.00009635108,0.0004467019,0.000233256,0.0001177034,0.0001686099],"domain_scores_gemma":[0.9995547,0.00001421511,0.0001232507,0.0001502546,0.00009434532,0.00006324182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003763992,0.00004483809,0.3301682,0.0003362859,0.000003468016,0.0000828487,0.000617573,0.000001758405,0.6626279,0.00003905686,0.00008740355,0.005952985],"study_design_scores_gemma":[0.002223118,0.001128437,0.5731386,0.001507774,0.00003831204,0.0002347038,0.001265517,0.0002420201,0.4200298,0.00004635805,0.00001433193,0.0001310001],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970396,0.001747562,0.00003385134,0.0003730302,0.00005587465,0.0001867445,0.00002728375,0.00000710262,0.0005289273],"genre_scores_gemma":[0.9988574,0.00008099512,0.0002940184,0.00009222332,0.0000371485,0.00001063205,0.0001610074,0.00001296091,0.0004535571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2429704,"threshold_uncertainty_score":0.5097197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679592754282348,"score_gpt":0.2368836909766975,"score_spread":0.220087763433874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}