{"id":"W3201114711","doi":"10.1074/jbc.a112.418830","title":"The intermediate filament vimentin mediates microRNA miR-378 function in cellular self-renewal by regulating the expression of the Sox2 transcription factor.","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Natural Science Foundation of China","keywords":"Vimentin; Transcription factor; microRNA; Cell biology; Intermediate filament; SOX2; Biology; Function (biology); Cell; Genetics; Cytoskeleton; Gene; Immunohistochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002048035,0.0003040301,0.0002075599,0.0001985188,0.000335143,0.000472274,0.0002581014,0.0002872854,0.004885579],"category_scores_gemma":[0.0003661092,0.0002278464,0.0002701253,0.0001131227,0.0002207082,0.0004098506,0.0003255792,0.0005161579,0.001926906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000313429,"about_ca_system_score_gemma":0.0002537431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005826468,"about_ca_topic_score_gemma":0.0009861571,"domain_scores_codex":[0.9998463,0.00002671192,0.00001560963,0.00003296928,0.00005064462,0.00002766339],"domain_scores_gemma":[0.9998541,0.00002808047,0.00004100325,0.00001609075,0.00002588054,0.00003481613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004378087,0.00002382096,0.001176214,0.0001633581,0.00001437695,0.0003027381,0.00006624359,0.00009949938,0.9823184,0.001408149,0.002144583,0.01184478],"study_design_scores_gemma":[0.00003756496,0.0001454371,0.01594629,0.00003581982,0.00004698052,0.0007605077,0.0001098258,0.002157509,0.9611377,0.0004652278,0.01914379,0.00001341135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396902,0.01667387,0.01683755,0.00134063,0.0008143892,0.0001118844,0.002352662,0.0008411916,0.02133769],"genre_scores_gemma":[0.9850864,0.002394167,0.00368654,0.0001470739,0.00005288004,0.00003471155,0.001117839,0.000105029,0.00737544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004885579,"threshold_uncertainty_score":0.01634389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01108726534325309,"score_gpt":0.2328224976374816,"score_spread":0.2217352322942285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}