{"id":"W3201310026","doi":"10.3390/molecules26185540","title":"(−)-6-epi-Artemisinin, a Natural Stereoisomer of (+)-Artemisinin in the Opposite Enantiomeric Series, from the Endemic Madagascar Plant Saldinia proboscidea, an Atypical Source","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"Malaria Research and Control","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Artemisinin; Artemisia annua; Natural product; Enantiomer; Absolute configuration; Stereochemistry; Biology; Chemical structure; Artemisia; Sesquiterpene; Chemistry; Botany; Malaria; Plasmodium falciparum; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004596628,0.0002303547,0.0001064358,0.000213814,0.0001184546,0.0001424775,0.0000942963,0.0001132585,0.001463566],"category_scores_gemma":[0.00007357387,0.00005448984,0.00008873655,0.0001823459,0.0001479881,0.0001537837,0.0001181113,0.0002826451,0.0002207619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000941608,"about_ca_system_score_gemma":0.0001496495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003324746,"about_ca_topic_score_gemma":0.0009146756,"domain_scores_codex":[0.9999712,0.00000585379,0.000002698899,0.000007025224,0.000007988823,0.000005268891],"domain_scores_gemma":[0.9999678,0.000003322067,0.00001110832,0.000004119526,0.000005569063,0.000008019253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001383916,0.00002275752,0.0006275835,0.0001035025,0.000008564522,0.0003250646,0.00003622179,0.00008656157,0.9875259,0.000281957,0.00008014894,0.01076318],"study_design_scores_gemma":[0.00002777575,0.0007286629,0.01154415,0.00001358072,0.00003175002,0.001940273,0.00007416806,0.0003206599,0.9648464,0.0002208489,0.02023959,0.00001226442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798893,0.003872299,0.005411882,0.0002372147,0.00006729832,0.00008376034,0.0009631076,0.00006195674,0.009413128],"genre_scores_gemma":[0.992085,0.001448257,0.003844263,0.000124575,0.00002553801,0.00001358061,0.0006430139,0.000008959829,0.001806722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463566,"threshold_uncertainty_score":0.004896104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600151819550276,"score_gpt":0.2616808993649662,"score_spread":0.2456793811694634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}