{"id":"W3201316389","doi":"10.3389/fcell.2021.729338","title":"Approaches to Study Native Chromatin-Modifying Complex Activities and Functions","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chromatin; Computational biology; Neuroscience; Biology; Computer science; Cell biology; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008410945,0.0005592476,0.0004053026,0.0005371253,0.0005250971,0.0006982959,0.0006829248,0.000533456,0.001950219],"category_scores_gemma":[0.0005173541,0.0004407008,0.0004361493,0.0004058571,0.0005647197,0.0007474494,0.0007268705,0.001869791,0.00108545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007474963,"about_ca_system_score_gemma":0.0005108402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007495579,"about_ca_topic_score_gemma":0.001619447,"domain_scores_codex":[0.9996402,0.00007770828,0.00003479452,0.0001018986,0.0001066394,0.00003873433],"domain_scores_gemma":[0.9995658,0.0001606127,0.00006926787,0.0001154308,0.00005566621,0.00003331899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002609262,0.00003232214,0.0001279234,0.0001249995,0.000009398388,0.00002952483,0.00003807139,0.0001281182,0.9946432,0.001483342,0.00008119117,0.003275858],"study_design_scores_gemma":[0.00001655078,0.0001505463,0.001117553,0.00001697904,0.00002686747,0.0002516144,0.00004441164,0.001273341,0.9742628,0.001010481,0.02181347,0.00001548243],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.3192164,0.01534758,0.6478472,0.001048498,0.0003521395,0.0007745632,0.002231681,0.001001281,0.01218069],"genre_scores_gemma":[0.4890835,0.01913786,0.4701296,0.0007738482,0.0001354697,0.001624738,0.004699022,0.0004891863,0.01392686],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001950219,"threshold_uncertainty_score":0.006524086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03563911919054991,"score_gpt":0.226853111955751,"score_spread":0.1912139927652011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}