{"id":"W3201555535","doi":"10.1128/mbio.00994-21","title":"Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding Yeast","year":2021,"lang":"en","type":"article","venue":"mBio","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Budding yeast; Vacuole; Polyphosphate; Yeast; Budding; Cell biology; Saccharomyces cerevisiae; Chemistry; Biology; Biochemistry; Cytoplasm; Phosphate","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006968864,0.0002165977,0.0001374998,0.0002080124,0.0002999187,0.0005341537,0.0002619492,0.0002418906,0.0009232418],"category_scores_gemma":[0.00008662206,0.0001163576,0.0002434644,0.0001623141,0.0001772506,0.000181858,0.0003244646,0.0003408194,0.0004776412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006772378,"about_ca_system_score_gemma":0.0002416633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002434175,"about_ca_topic_score_gemma":0.002084549,"domain_scores_codex":[0.9999335,0.000006481765,0.000008535978,0.00002239582,0.00001807532,0.00001091219],"domain_scores_gemma":[0.9999489,0.000005889131,0.00001437428,0.000005590712,0.000007647342,0.00001765065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000124852,0.000009339946,0.0007044364,0.00004630565,0.000007437504,0.0002486348,0.00003857502,0.0001638637,0.9957547,0.0009101061,0.0001736953,0.001817907],"study_design_scores_gemma":[0.00003132504,0.00003755314,0.01611421,0.00003242196,0.00002767221,0.0007102618,0.000192356,0.006366676,0.9638622,0.0004567759,0.01215186,0.00001670221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9783561,0.003989173,0.01352909,0.0002507074,0.0001117505,0.0000214977,0.001507194,0.0001967266,0.002037775],"genre_scores_gemma":[0.992619,0.0006994671,0.003038856,0.00007214262,0.00000431538,0.00001164749,0.001234071,0.00004496167,0.002275687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002434175,"threshold_uncertainty_score":0.004913747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02990782566766462,"score_gpt":0.2769385421321604,"score_spread":0.2470307164644958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}