{"id":"W3201667309","doi":"10.1016/j.euroneuro.2021.08.150","title":"W65. EVALUATING TREATMENT OUTCOMES IN PHARMACOGENOMIC-GUIDED CARE FOR MAJOR DEPRESSION: A RAPID REVIEW AND META-ANALYSIS","year":2021,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacogenomics; Pharmacogenetics; Medicine; Pharmacology; Drug; Bioinformatics; Intensive care medicine; Biology; Gene; Genetics; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009913449,0.002114207,0.01277653,0.003193829,0.0002711644,0.002721582,0.001594522,0.001813672,0.007241486],"category_scores_gemma":[0.0218374,0.0009521922,0.01833688,0.003975824,0.0003451439,0.001546218,0.001520788,0.00173454,0.0007658781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001277937,"about_ca_system_score_gemma":0.002960324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003237844,"about_ca_topic_score_gemma":0.009591244,"domain_scores_codex":[0.9949307,0.002295804,0.001425948,0.0005955123,0.0005894318,0.0001624919],"domain_scores_gemma":[0.9906448,0.006480337,0.001751892,0.0002969289,0.0007101294,0.0001158687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002980748,0.00006536733,0.00235685,0.5220144,0.2847381,0.000126814,0.00006579317,0.0006111454,0.0006728469,0.000432362,0.005609496,0.1803261],"study_design_scores_gemma":[0.004127648,0.0006613255,0.00918644,0.113912,0.8353258,0.0002537034,0.00007603761,0.0006110849,0.0003834294,0.001306503,0.03403408,0.0001218819],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005414034,0.9977027,0.0004261291,0.0002812696,0.0002198284,0.0001340474,0.0004570545,0.00002157308,0.0002160492],"genre_scores_gemma":[0.02395563,0.9693004,0.00268085,0.002015464,0.0004347426,0.0003977259,0.0007946976,0.00003311692,0.0003873204],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01277653,"threshold_uncertainty_score":0.05242795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4100655715963766,"score_gpt":0.5511010450781461,"score_spread":0.1410354734817694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}