{"id":"W3201797936","doi":"10.1038/s41398-021-01600-7","title":"Barriers to clinical adoption of pharmacogenomic testing in psychiatry: a critical analysis","year":2021,"lang":"en","type":"review","venue":"Translational Psychiatry","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Reimbursement; Pharmacogenomics; Context (archaeology); Stakeholder; Health care; Commercialization; Psychology; Medicine; Business; Political science; Public relations; Marketing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03890036,0.0005946105,0.001961361,0.003915553,0.0006051248,0.003829454,0.001945198,0.002252575,0.002007432],"category_scores_gemma":[0.08242431,0.0004994243,0.00158832,0.004019455,0.001619203,0.004618051,0.001773383,0.003818519,0.0003827242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004985881,"about_ca_system_score_gemma":0.01627904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005017373,"about_ca_topic_score_gemma":0.01140119,"domain_scores_codex":[0.9831411,0.008559085,0.003056237,0.0008294666,0.003994629,0.0004195754],"domain_scores_gemma":[0.8493029,0.1293744,0.006535222,0.001244947,0.0128523,0.0006902376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001186238,0.00004265117,0.001393981,0.1103311,0.0007021365,0.0002785378,0.001158241,0.0004662296,0.000234575,0.01413756,0.01893927,0.8521971],"study_design_scores_gemma":[0.00008352615,0.0002507125,0.007006329,0.362448,0.003003095,0.001638851,0.003069674,0.0006163018,0.0006799353,0.01268377,0.6084086,0.0001112504],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003828458,0.9883767,0.0002859725,0.009953156,0.0002486188,0.00003044784,0.00002924813,0.000004652765,0.0006884681],"genre_scores_gemma":[0.006234221,0.9895069,0.0008884341,0.002895637,0.0002743746,0.00006088505,0.00003314635,0.00000405151,0.0001024275],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03890036,"threshold_uncertainty_score":0.2057272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2879405508504725,"score_gpt":0.5638701600992077,"score_spread":0.2759296092487351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}