{"id":"W3202091259","doi":"10.1007/s11302-021-09819-1","title":"Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation","year":2021,"lang":"en","type":"article","venue":"Purinergic Signalling","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Instituto Nacional de Ciência e Tecnologia da Criosfera; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Sepsis; Inflammation; Immunology; Immune system; Lipopolysaccharide; Extracellular; Biology; Downregulation and upregulation; Neutrophil extracellular traps; Systemic inflammation; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001657201,0.0001633136,0.0002493752,0.0003197317,0.0001526699,0.0004213152,0.00006687864,0.0002862899,0.0009668266],"category_scores_gemma":[0.0002850724,0.0001505114,0.0001515445,0.0002546179,0.0001869336,0.000162972,0.0002005537,0.0002450387,0.0002173591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001219745,"about_ca_system_score_gemma":0.0001039508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002271497,"about_ca_topic_score_gemma":0.0004320069,"domain_scores_codex":[0.9998379,0.00003981409,0.00001450211,0.00003227286,0.00002823541,0.00004720359],"domain_scores_gemma":[0.999851,0.00003030708,0.0000557019,0.00001605281,0.00002030758,0.00002671164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001212376,0.00001332397,0.002432342,0.0000368362,0.000009558788,0.0002056864,0.00007476356,0.00004246894,0.994022,0.0001167095,0.00003463283,0.001799324],"study_design_scores_gemma":[0.00008095347,0.001074995,0.2975673,0.00003143738,0.00009421985,0.002208762,0.0004963936,0.0008405295,0.692704,0.0003318196,0.004551657,0.00001807236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946865,0.002898543,0.001196038,0.00005694239,0.00001654719,0.00001313995,0.0004216587,0.00001440905,0.0006962096],"genre_scores_gemma":[0.996662,0.0008102282,0.000855295,0.00003963729,0.00001189154,0.00003375712,0.0004885402,0.000004952018,0.001093634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009668266,"threshold_uncertainty_score":0.003234327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0085989312572735,"score_gpt":0.2221568945809435,"score_spread":0.21355796332367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}