{"id":"W3202091259","doi":"10.1007/s11302-021-09819-1","title":"Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation","year":2021,"lang":"en","type":"article","venue":"Purinergic Signalling","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Instituto Nacional de Ciência e Tecnologia da Criosfera; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Sepsis; Inflammation; Immunology; Immune system; Lipopolysaccharide; Extracellular; Biology; Downregulation and upregulation; Neutrophil extracellular traps; Systemic inflammation; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001265927,0.0002686619,0.0002890013,0.0001227115,0.0001853306,0.0001009974,0.0001012431,0.0001561316,0.0001232814],"category_scores_gemma":[0.000055229,0.0002860941,0.00006040373,0.000159384,0.0000722137,0.00001984659,0.0002197298,0.0001463157,0.000002157866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001632063,"about_ca_system_score_gemma":0.00002455429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000974226,"about_ca_topic_score_gemma":0.00006061097,"domain_scores_codex":[0.9984704,0.00009427749,0.0003907171,0.0005603356,0.0001602778,0.000323976],"domain_scores_gemma":[0.9994121,0.00002602327,0.0001470821,0.0002201726,0.00008109445,0.0001135617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005503905,0.00004696927,0.02049124,0.0001193685,0.00005887528,0.0002159535,0.0001288629,0.001250383,0.9772413,0.0001313092,0.00004529998,0.0002153876],"study_design_scores_gemma":[0.001362165,0.00008091387,0.05012203,0.0002362853,0.0000383372,0.000126292,0.0002934553,0.0005820871,0.9458767,0.0001370137,0.0007132462,0.0004314466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798665,0.01958057,0.0001069357,0.0001635035,0.00003711214,0.0001165449,0.00000444593,0.00003678066,0.00008761789],"genre_scores_gemma":[0.9970182,0.0007578593,0.0003296324,0.00002035926,0.0003423452,0.00001174178,0.0001068923,0.00004822047,0.001364728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03136458,"threshold_uncertainty_score":0.9999591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0085989312572735,"score_gpt":0.2221568945809435,"score_spread":0.21355796332367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}