{"id":"W3202210649","doi":"10.1007/s12033-021-00389-6","title":"Production and Use of Gesicles for Nucleic Acid Delivery","year":2021,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Université Laval; Hôpital de l'Enfant-Jésus; PROTEO","funders":"","keywords":"Nucleic acid; Transfection; Green fluorescent protein; Plasmid; Biology; Molecular biology; Polyethylenimine; DNA; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003882991,0.0005384337,0.0002967349,0.0003966752,0.0003164396,0.000404118,0.0002915065,0.0004003032,0.0006052765],"category_scores_gemma":[0.0002999799,0.000236936,0.0004570836,0.000321397,0.0003352223,0.000299875,0.0005134808,0.000590514,0.0007153487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003916996,"about_ca_system_score_gemma":0.0002990995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000445966,"about_ca_topic_score_gemma":0.0006488477,"domain_scores_codex":[0.9997324,0.00003234093,0.00002777459,0.00005642532,0.000108736,0.00004238056],"domain_scores_gemma":[0.999779,0.00003405608,0.00005738816,0.00006427844,0.00003682958,0.00002839539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000145761,0.000005751677,0.00004178749,0.00001745617,0.000002982656,0.00002525352,0.000009487417,0.00007883094,0.9985934,0.0001607828,0.00001264291,0.001037097],"study_design_scores_gemma":[0.000001483055,0.00002036122,0.0002263905,0.00000245752,0.000003531766,0.00005535523,0.000003158834,0.0001210759,0.997404,0.00004005392,0.002120635,0.000001411551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8353733,0.005636344,0.1472724,0.0003264999,0.0001489788,0.0003949157,0.001670133,0.0006055051,0.008571888],"genre_scores_gemma":[0.8570302,0.005374662,0.1186344,0.0001042932,0.00002208851,0.0002904717,0.004206524,0.000291182,0.01404615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006052765,"threshold_uncertainty_score":0.002842069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01318959041734646,"score_gpt":0.228186641681477,"score_spread":0.2149970512641305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}