{"id":"W3202460246","doi":"10.1056/nejmoa2033617","title":"Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis","year":2021,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":532,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Bristol-Myers Squibb","keywords":"Medicine; Internal medicine; Placebo; Ulcerative colitis; Cohort; Maintenance therapy; Population; Clinical endpoint; Clinical trial; Surgery; Disease; Pathology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002793534,0.00007105818,0.0001235331,0.00002314653,0.00003600633,0.000007004018,0.0000407496,0.00004803546,0.0000445501],"category_scores_gemma":[0.0003648799,0.00005088641,0.00003438818,0.0000262087,0.0000541618,0.000004809201,0.000009727602,0.00007008714,3.688553e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008555503,"about_ca_system_score_gemma":0.0002136739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005062393,"about_ca_topic_score_gemma":0.00003245793,"domain_scores_codex":[0.9994793,0.00006024392,0.0001752516,0.00009553706,0.00009781946,0.00009187344],"domain_scores_gemma":[0.9993625,0.00002046237,0.0001161306,0.00007440523,0.0003003445,0.0001262168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01723537,0.0001209286,0.005201155,0.00006938538,0.0004727055,0.001054165,0.001694236,0.00003365409,0.555283,0.002671347,0.06414738,0.3520167],"study_design_scores_gemma":[0.1158006,0.004721179,0.2054741,0.0002848048,0.0001192633,0.00416435,0.001214026,0.00002775846,0.07907775,0.008154244,0.58066,0.0003018238],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933268,0.001396261,0.001430852,0.002916771,0.0003405995,0.00008931211,0.00000423422,0.00000149861,0.0004936908],"genre_scores_gemma":[0.9925267,0.001690197,0.0004269962,0.0009346794,0.003474454,0.000002341623,0.00001397839,0.000009400104,0.0009212206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5165127,"threshold_uncertainty_score":0.2075087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01157596818345418,"score_gpt":0.2696668806602484,"score_spread":0.2580909124767942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}