{"id":"W3202460246","doi":"10.1056/nejmoa2033617","title":"Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis","year":2021,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":532,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Bristol-Myers Squibb","keywords":"Medicine; Internal medicine; Placebo; Ulcerative colitis; Cohort; Maintenance therapy; Population; Clinical endpoint; Clinical trial; Surgery; Disease; Pathology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001318688,0.0004254131,0.001190066,0.0003392693,0.0002358049,0.0003856206,0.0005719204,0.0006510433,0.00207864],"category_scores_gemma":[0.0008994348,0.0001806513,0.0005122235,0.0003071838,0.0004419047,0.0004000404,0.0003699561,0.00120387,0.0002384514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003417649,"about_ca_system_score_gemma":0.0006501126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002149006,"about_ca_topic_score_gemma":0.0006368006,"domain_scores_codex":[0.999554,0.0002004819,0.00004902503,0.0000563853,0.00007744782,0.00006265639],"domain_scores_gemma":[0.999167,0.000197524,0.0002827218,0.00005900495,0.00003973774,0.0002539426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6986087,0.0169597,0.01184622,0.001643999,0.0007563257,0.000182807,0.0001752408,0.000578273,0.03488981,0.0001681864,0.0007851327,0.2334056],"study_design_scores_gemma":[0.3162484,0.6231102,0.04766434,0.0001819702,0.0007269061,0.0003754249,0.00007249064,0.0008281776,0.00790354,0.00009518026,0.00276275,0.00003074697],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993903,0.004702505,0.0002236315,0.0001478109,0.00005655952,0.000344671,0.0001126014,0.00003362148,0.0004755945],"genre_scores_gemma":[0.995509,0.002231701,0.0008406691,0.0002254408,0.0001248317,0.0003951642,0.0002808882,0.00000450238,0.0003877597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00207864,"threshold_uncertainty_score":0.006973982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01157596818345418,"score_gpt":0.2696668806602484,"score_spread":0.2580909124767942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}