{"id":"W3202475565","doi":"10.1080/15412555.2021.1982886","title":"Triple Therapy in COPD: Time for Adaptive Selection Trials","year":2021,"lang":"en","type":"article","venue":"COPD Journal of Chronic Obstructive Pulmonary Disease","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Medicine; Clinical trial; COPD; Intensive care medicine; Selection (genetic algorithm); Adaptive design; Physical therapy; Internal medicine; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2291054,0.001727451,0.004512291,0.001407798,0.001760719,0.00631789,0.003593001,0.009356818,0.009205847],"category_scores_gemma":[0.352547,0.001126486,0.004926497,0.002565883,0.00537659,0.01440047,0.004845734,0.01280181,0.002023317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002953179,"about_ca_system_score_gemma":0.006117316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004840848,"about_ca_topic_score_gemma":0.0005218255,"domain_scores_codex":[0.646947,0.3162518,0.0159078,0.007761386,0.01184556,0.001286488],"domain_scores_gemma":[0.6451256,0.2761417,0.02909473,0.03463092,0.009527188,0.005479774],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.07009202,0.001622268,0.005221533,0.02437694,0.008810778,0.0004224318,0.002387315,0.005636607,0.001485837,0.1621533,0.04467308,0.6731179],"study_design_scores_gemma":[0.1773679,0.0230558,0.005143665,0.02382297,0.006198317,0.0007968571,0.0005854488,0.01390461,0.002002396,0.5283461,0.2183108,0.0004651514],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"commentary","genre_scores_codex":[0.03839196,0.2458319,0.2942422,0.2885851,0.05652542,0.04626412,0.001580342,0.001909731,0.02666917],"genre_scores_gemma":[0.2689265,0.04202558,0.3727176,0.1459497,0.02269913,0.1396804,0.001044075,0.0006822547,0.006274748],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.7708946,"threshold_uncertainty_score":0.9506503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03524150845972297,"score_gpt":0.3238913858546068,"score_spread":0.2886498773948838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}