{"id":"W3202516202","doi":"10.1016/j.annonc.2021.08.1169","title":"726MO Outcomes by histology and prior therapy with lenvatinib plus pembrolizumab vs treatment of physician’s choice in patients with advanced endometrial cancer (Study 309/KEYNOTE-775)","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Merck Sharp and Dohme","keywords":"Medicine; Pembrolizumab; Internal medicine; Population; Endometrial cancer; Cervical cancer; Lenvatinib; Oncology; Gynecology; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001309279,0.0008066637,0.001332785,0.0004331846,0.0005593176,0.001147393,0.0009359524,0.001429321,0.01207868],"category_scores_gemma":[0.002756511,0.0006627154,0.008096606,0.0006029725,0.0004168168,0.001334689,0.0009733268,0.003542098,0.0008696155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001226906,"about_ca_system_score_gemma":0.001907182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01160504,"about_ca_topic_score_gemma":0.02520968,"domain_scores_codex":[0.9989986,0.0003472995,0.00006414745,0.0002251241,0.00006496168,0.0002998887],"domain_scores_gemma":[0.9985186,0.0004414548,0.0004443003,0.0001062267,0.00007709994,0.0004122207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.661167,0.004097139,0.2585792,0.001938862,0.02743815,0.0002738642,0.0002280366,0.002235807,0.001801085,0.0007283785,0.0160759,0.02543662],"study_design_scores_gemma":[0.1666123,0.08253697,0.6944838,0.001004023,0.03232242,0.0004752451,0.001091251,0.004134433,0.001363826,0.002029346,0.01373706,0.0002094479],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771563,0.006559453,0.0002379555,0.0008665082,0.0006937343,0.0002204083,0.0101338,0.00003144422,0.00410032],"genre_scores_gemma":[0.9872054,0.001270395,0.0002560074,0.001019206,0.000434081,0.0002848102,0.004760826,0.00001334547,0.0047558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01207868,"threshold_uncertainty_score":0.04040718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05284778229844425,"score_gpt":0.3777825332580952,"score_spread":0.324934750959651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}