{"id":"W3202609465","doi":"10.1016/j.annonc.2021.08.1230","title":"788P Circulating human papillomavirus DNA as a biomarker of response in advanced cervical cancer","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Cervical cancer; Biomarker; Oncology; Human papillomavirus; Cancer; Internal medicine; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006526535,0.0003435301,0.0004359631,0.001309148,0.0003364479,0.0009751419,0.0003779379,0.0008548998,0.002459212],"category_scores_gemma":[0.002940927,0.0001781483,0.0001429805,0.0008000676,0.0003451974,0.0003535731,0.0003429501,0.0006670064,0.0006946566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004929655,"about_ca_system_score_gemma":0.0002817119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203264,"about_ca_topic_score_gemma":0.001125804,"domain_scores_codex":[0.9996253,0.00009044228,0.00002387587,0.00007144883,0.0001275123,0.00006142311],"domain_scores_gemma":[0.9988726,0.0004937127,0.0002014449,0.00005204547,0.0002046291,0.0001756118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003619021,0.0002992231,0.8846704,0.0001201646,0.0001093671,0.00105876,0.0003068598,0.0005809157,0.05367683,0.0002088178,0.001208189,0.05414133],"study_design_scores_gemma":[0.00009247525,0.002018737,0.9607098,0.00005241681,0.0001392571,0.003946702,0.000631491,0.004787101,0.02205352,0.0007479846,0.004794301,0.00002611697],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950288,0.001273844,0.0003649517,0.000281312,0.00007250794,0.00001729059,0.0004431927,0.00003817273,0.00248009],"genre_scores_gemma":[0.9976876,0.0002842602,0.0005462573,0.00009194984,0.00005401454,0.00002083739,0.0002827329,0.000008113944,0.001024291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002459212,"threshold_uncertainty_score":0.008226812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05592361801114772,"score_gpt":0.4011737761867957,"score_spread":0.345250158175648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}