{"id":"W3202618401","doi":"10.1097/dss.0000000000003238","title":"Efficacy and Safety of a New Resilient Hyaluronic Acid Filler in the Correction of Moderate-to-Severe Dynamic Perioral Rhytides: A 52-Week Prospective, Multicenter, Controlled, Randomized, Evaluator-Blinded Study.","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"Facial Rejuvenation and Surgery Techniques","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada); Institute of Cosmetic and Laser Surgery","funders":"","keywords":"Medicine; Wrinkle; Patient satisfaction; Hyaluronic acid; Randomized controlled trial; Adverse effect; Multicenter study; Clinical endpoint; Clinical trial; Dermatology; Dentistry; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005281033,0.001432838,0.002878607,0.0006428947,0.0005886845,0.0009369624,0.001361568,0.002166305,0.003335001],"category_scores_gemma":[0.002784057,0.0009100807,0.001451265,0.0004713689,0.001785801,0.001374442,0.0004268581,0.001902151,0.0006844746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004359666,"about_ca_system_score_gemma":0.0009681978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002961914,"about_ca_topic_score_gemma":0.0006096329,"domain_scores_codex":[0.9977325,0.001227708,0.0002129716,0.0004216262,0.0002360974,0.0001689519],"domain_scores_gemma":[0.9974872,0.000926426,0.0007194561,0.0003099449,0.0001917469,0.0003652668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8718485,0.06671326,0.001269755,0.001086087,0.0008317533,0.0000816625,0.0002008441,0.0004212035,0.02804935,0.0001037751,0.0003754405,0.02901834],"study_design_scores_gemma":[0.5196835,0.4738037,0.002728833,0.00003026156,0.0003453778,0.00005372855,0.00003244029,0.0003910644,0.002469795,0.00004333479,0.0003972474,0.00002078786],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914806,0.001909228,0.001095254,0.0001412415,0.0001749309,0.004291688,0.0002951999,0.00007916796,0.000532743],"genre_scores_gemma":[0.9902993,0.00103901,0.003006256,0.0003310025,0.0003776424,0.003780685,0.0002739911,0.0000261016,0.0008659114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005281033,"threshold_uncertainty_score":0.02792907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02381005379655814,"score_gpt":0.2938991904396005,"score_spread":0.2700891366430423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}