{"id":"W3202618401","doi":"10.1097/dss.0000000000003238","title":"Efficacy and Safety of a New Resilient Hyaluronic Acid Filler in the Correction of Moderate-to-Severe Dynamic Perioral Rhytides: A 52-Week Prospective, Multicenter, Controlled, Randomized, Evaluator-Blinded Study.","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"Facial Rejuvenation and Surgery Techniques","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada); Institute of Cosmetic and Laser Surgery","funders":"","keywords":"Medicine; Wrinkle; Patient satisfaction; Hyaluronic acid; Randomized controlled trial; Adverse effect; Multicenter study; Clinical endpoint; Clinical trial; Dermatology; Dentistry; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003088442,0.0001664615,0.0009446525,0.000321788,0.000100612,0.00001549052,0.0001080597,0.00004281597,0.00006844861],"category_scores_gemma":[0.001980305,0.0001167221,0.0001655623,0.0004490951,0.00007706763,0.00005449391,0.00008147298,0.0002790577,5.330064e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000276664,"about_ca_system_score_gemma":0.0001775477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002315852,"about_ca_topic_score_gemma":0.0001516277,"domain_scores_codex":[0.9972718,0.0008125358,0.0007258239,0.0003012757,0.0006431249,0.0002453818],"domain_scores_gemma":[0.9988034,0.0004526757,0.0002388277,0.0002587708,0.0001496351,0.00009663663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8951465,0.00301144,0.007749668,0.00003487754,0.0002707061,0.00001644903,0.01044496,0.0007967848,0.0001749838,0.00007103116,0.0007785888,0.08150403],"study_design_scores_gemma":[0.6298451,0.001138418,0.3379264,0.00006501866,0.0002518604,0.0000262925,0.005665013,0.02379342,0.0002893994,0.00009894271,0.0006850082,0.0002151184],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820288,0.0003970448,0.000157706,0.00100984,0.0002216229,0.01546157,0.00001050651,0.00004067212,0.0006722403],"genre_scores_gemma":[0.9932562,0.00003966811,0.00006313564,0.0002799265,0.000008329578,0.005622901,0.000006879923,0.00001681095,0.0007061277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3301767,"threshold_uncertainty_score":0.475979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02381005379655814,"score_gpt":0.2938991904396005,"score_spread":0.2700891366430423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}