{"id":"W3202782750","doi":"10.1016/j.annonc.2021.08.2137","title":"LBA57 Unicancer PRODIGE 24/CCTG PA6 trial: Updated results of a multicenter international randomized phase III trial of adjuvant mFOLFIRINOX (mFFX) versus gemcitabine (gem) in patients (pts) with resected pancreatic ductal adenocarcinomas (PDAC)","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Gemcitabine; Internal medicine; Pancreatic ductal adenocarcinoma; Oncology; Gastroenterology; Pancreatic cancer; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002345285,0.001253737,0.002488985,0.0003783889,0.000332911,0.001325127,0.0008329719,0.001019776,0.005083099],"category_scores_gemma":[0.001720486,0.0004362493,0.002246276,0.0004954323,0.0007821788,0.001047715,0.0004955055,0.003395739,0.001208416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001061097,"about_ca_system_score_gemma":0.001253811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001165013,"about_ca_topic_score_gemma":0.003671928,"domain_scores_codex":[0.9993421,0.0003820896,0.000029141,0.0001063794,0.00004715158,0.00009295279],"domain_scores_gemma":[0.999257,0.0001703175,0.0001922825,0.00007980107,0.00005158825,0.0002489603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9048444,0.003404253,0.003210766,0.0009838918,0.003037246,0.00007478457,0.00008261667,0.001146102,0.006235907,0.0003620485,0.006155767,0.07046209],"study_design_scores_gemma":[0.913998,0.0640735,0.00998703,0.0001265176,0.003346091,0.0001791134,0.00005578946,0.0009145782,0.00100054,0.0004329809,0.005845579,0.00004025748],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656544,0.01570563,0.001182237,0.002769761,0.0007487454,0.001723154,0.005318882,0.0003178187,0.00657938],"genre_scores_gemma":[0.9667994,0.006060366,0.003305818,0.003099811,0.0006389235,0.002164541,0.01147672,0.0001304738,0.006323956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005083099,"threshold_uncertainty_score":0.01700461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09165052601406397,"score_gpt":0.4167157518229661,"score_spread":0.3250652258089021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}