{"id":"W3202954574","doi":"10.3390/v13101929","title":"Primary HSV-2 Infection in Early Pregnancy Results in Transplacental Viral Transmission and Dose-Dependent Adverse Pregnancy Outcomes in a Novel Mouse Model","year":2021,"lang":"en","type":"article","venue":"Viruses","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"Pregnancy; Transplacental; Fetus; In utero; Herpes simplex virus; Medicine; Immunology; Viral shedding; Gestation; Placenta; Viral load; Inflammation; Andrology; Physiology; Biology; Virology; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008340405,0.001267011,0.0007554949,0.001733472,0.0005025616,0.0009336643,0.0009752533,0.001363173,0.002473463],"category_scores_gemma":[0.0003637398,0.0008296085,0.0009192221,0.0004414909,0.0007776979,0.0006250506,0.0005771288,0.003393795,0.0008150611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007439155,"about_ca_system_score_gemma":0.0005541462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0012133,"about_ca_topic_score_gemma":0.002006061,"domain_scores_codex":[0.9990594,0.0001375032,0.0001250374,0.0002745078,0.0002449303,0.0001586343],"domain_scores_gemma":[0.9993063,0.00009063641,0.0002320301,0.0001185466,0.00004524451,0.0002071385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008055633,0.0006019436,0.000721264,0.0001097091,0.00002309531,0.0003438473,0.000111718,0.000173474,0.9940045,0.000450758,0.0002105811,0.002443524],"study_design_scores_gemma":[0.0002716858,0.006655804,0.01206788,0.0001116683,0.0001444813,0.003126302,0.0002266321,0.002893275,0.9654627,0.0005451722,0.008437759,0.00005664781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720579,0.004242135,0.01410061,0.0006678935,0.0002445779,0.0004827716,0.003891676,0.0005688717,0.003743496],"genre_scores_gemma":[0.9430302,0.006412481,0.02123894,0.0005395882,0.00009175023,0.001428491,0.00395918,0.0002617573,0.02303757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002473463,"threshold_uncertainty_score":0.008274615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03133918953707521,"score_gpt":0.2931012642641132,"score_spread":0.261762074727038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}