{"id":"W3202997693","doi":"10.1016/j.ejca.2021.08.013","title":"Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006","year":2021,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Pembrolizumab; Medicine; Internal medicine; Post-hoc analysis; Melanoma; Gastroenterology; Surgery; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002323469,0.0003151793,0.0008947274,0.0002860018,0.0004373536,0.0006065918,0.0002761829,0.00058684,0.0009539088],"category_scores_gemma":[0.001930047,0.0001877729,0.00144633,0.000328703,0.000333535,0.0007113395,0.0005123216,0.000783755,0.000175138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004800853,"about_ca_system_score_gemma":0.0003921347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004973614,"about_ca_topic_score_gemma":0.001027121,"domain_scores_codex":[0.9993243,0.0003196038,0.00004917309,0.00009072833,0.00007932386,0.000136849],"domain_scores_gemma":[0.9984597,0.0004150014,0.0005155289,0.0001005653,0.0001067216,0.0004024283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.09891924,0.00195438,0.8730268,0.0001566359,0.00180907,0.0004941789,0.0002075785,0.001332042,0.004294394,0.00005450895,0.0004854236,0.01726576],"study_design_scores_gemma":[0.004452421,0.04521841,0.9446325,0.00004524846,0.001119155,0.0006585632,0.0002180154,0.001480221,0.001179185,0.00009932685,0.0008633289,0.00003352606],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993907,0.0003562924,0.00003596077,0.00002780821,0.000005958139,0.00001138599,0.0000767728,0.000001158148,0.0000940162],"genre_scores_gemma":[0.9991642,0.0001110999,0.00004991946,0.00004718843,0.00002393086,0.00002752241,0.0004464489,9.277498e-7,0.0001287155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002323469,"threshold_uncertainty_score":0.0122878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057411755757271,"score_gpt":0.2682504746834606,"score_spread":0.2576763571258879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}