{"id":"W3203037161","doi":"10.1038/s41578-021-00372-2","title":"Designing spatial and temporal control of vaccine responses","year":2021,"lang":"en","type":"review","venue":"Nature Reviews Materials","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":307,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Immune system; Vaccination; Immunity; Immunology; Computer science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001058466,0.001377691,0.001295729,0.0009552795,0.0002435707,0.001345012,0.001496713,0.001772127,0.002662456],"category_scores_gemma":[0.0009871197,0.0006802739,0.0003879272,0.001003767,0.00110675,0.002221221,0.001134102,0.002617797,0.002095406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001092606,"about_ca_system_score_gemma":0.0007248983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006301597,"about_ca_topic_score_gemma":0.0008500844,"domain_scores_codex":[0.9997095,0.00005466881,0.0000230939,0.00005484719,0.0001112648,0.00004645499],"domain_scores_gemma":[0.9997081,0.0001519064,0.00004401356,0.00002068201,0.00005556932,0.00001971245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001303624,0.0001150673,0.00009038806,0.0111021,0.00006365565,0.0001501526,0.00004963846,0.002469735,0.03169678,0.05060655,0.02868837,0.8748373],"study_design_scores_gemma":[0.00003825267,0.0001199547,0.0001761836,0.001212684,0.00005308123,0.0003361436,0.00002431441,0.001039984,0.01066401,0.01196914,0.9743416,0.00002468996],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003627683,0.9917356,0.003426407,0.0005659845,0.001053966,0.00002044619,0.00002347554,0.00004339436,0.002768],"genre_scores_gemma":[0.004147899,0.988674,0.00289156,0.0006872364,0.000584956,0.00004655969,0.00006338123,0.00001525108,0.002889277],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002662456,"threshold_uncertainty_score":0.008906782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805880848055576,"score_gpt":0.3273347497057044,"score_spread":0.2992759412251487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}