{"id":"W3203068775","doi":"10.3390/curroncol28050321","title":"Global DNA 5hmC and CK195hmC+ Contents: A Promising Biomarker for Predicting Prognosis in Small Hepatocellular Carcinoma","year":2021,"lang":"en","type":"article","venue":"Current Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Biomarker; Hepatocellular carcinoma; 5-Hydroxymethylcytosine; Lymph node metastasis; Internal medicine; Oncology; Medicine; Immunohistochemistry; Cancer research; Metastasis; Biology; Gene expression; Gene; DNA methylation; Cancer; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004359459,0.0004218485,0.0003439203,0.001476079,0.0001938934,0.0005138516,0.0002158846,0.0004062995,0.00126614],"category_scores_gemma":[0.0005527805,0.0001660119,0.0002597794,0.000741028,0.0002752951,0.0003334568,0.0003070134,0.00032683,0.0002490819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003340425,"about_ca_system_score_gemma":0.0002020146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007820111,"about_ca_topic_score_gemma":0.00132418,"domain_scores_codex":[0.9998515,0.00003030622,0.00001525833,0.00003614059,0.00003972073,0.00002710228],"domain_scores_gemma":[0.9996713,0.0000561726,0.0001364656,0.00002457268,0.00005849555,0.00005300107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00170903,0.00009052209,0.7317496,0.0003364842,0.0002509567,0.0003119836,0.0001122114,0.0006316472,0.2217873,0.0001588964,0.0003853616,0.04247611],"study_design_scores_gemma":[0.0000222819,0.0008832634,0.9077965,0.00005673979,0.0004158395,0.001352154,0.0002797551,0.003673584,0.08236136,0.0004680654,0.002659182,0.00003126487],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840789,0.01054539,0.003366326,0.0001478809,0.00002607485,0.00003757754,0.0006914591,0.00007126892,0.001035009],"genre_scores_gemma":[0.9961646,0.001188604,0.001657111,0.00004228537,0.00002434691,0.00002162023,0.0004763424,0.000005590969,0.0004195133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001476079,"threshold_uncertainty_score":0.004235685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2299549129762658,"score_gpt":0.3565512144031743,"score_spread":0.1265963014269085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}