{"id":"W3203164319","doi":"10.14309/ctg.0000000000000401","title":"Post-Induction High Adalimumab Drug Levels Predict Biological Remission at Week 24 in Patients With Crohn's Disease","year":2021,"lang":"en","type":"article","venue":"Clinical and Translational Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Adalimumab; Medicine; Crohn's disease; Internal medicine; Drug; Disease; Gastroenterology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001795259,0.0001618612,0.0001905129,0.00002998557,0.00007225545,0.000009252542,0.00007598364,0.0001458785,0.0000991827],"category_scores_gemma":[0.0001027158,0.0001306186,0.00009260043,0.00003322087,0.0002779276,0.000009803205,0.00007176674,0.0001582506,0.000004666646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007084493,"about_ca_system_score_gemma":0.00008853817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001907928,"about_ca_topic_score_gemma":0.00009443052,"domain_scores_codex":[0.9983013,0.0003278608,0.0004414106,0.0005455395,0.0001390112,0.0002449349],"domain_scores_gemma":[0.9993086,0.00003392423,0.00008321241,0.0001855657,0.000141582,0.0002470835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01214565,0.0005271687,0.9860483,0.00001427703,0.00004509893,0.0001559858,0.000008523109,0.00006494356,0.000364639,0.00003587402,0.0001030485,0.0004864623],"study_design_scores_gemma":[0.005126335,0.0004797183,0.9936228,0.00001833867,0.0000300145,0.000007524135,0.000005379688,0.00002733981,0.00004030795,0.000189667,0.0003533195,0.00009922652],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997835,0.00005680841,0.0001584103,0.001235929,0.000209194,0.0001851182,0.0002942662,0.00001074043,0.00001447376],"genre_scores_gemma":[0.9970289,0.00002835086,0.0003878588,0.0007987444,0.0001588275,0.00001619512,0.00143422,0.00001308535,0.0001338258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007574503,"threshold_uncertainty_score":0.5326472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690384646973515,"score_gpt":0.2498360464131201,"score_spread":0.2329321999433849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}