{"id":"W3203217087","doi":"10.1101/2021.03.28.437432","title":"Endocervical regulatory T cells are associated with decreased genital inflammation and lower HIV target cell abundance","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Medical Service Foundation","keywords":"FOXP3; Endocervix; Inflammation; Proinflammatory cytokine; Immunology; IL-2 receptor; Regulatory T cell; Context (archaeology); Biology; T cell; Internal medicine; Medicine; Immune system; Cervix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002922417,0.0003134855,0.0004227813,0.0004939867,0.0003371112,0.000890895,0.0002957388,0.0004633083,0.00493354],"category_scores_gemma":[0.001392222,0.0002671008,0.0002865693,0.0006183208,0.0002752132,0.0002092393,0.0002705199,0.0006922883,0.0004038991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573078,"about_ca_system_score_gemma":0.0002317989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002270812,"about_ca_topic_score_gemma":0.002235834,"domain_scores_codex":[0.9997824,0.00004668289,0.00001320898,0.00005680085,0.00004751033,0.00005332598],"domain_scores_gemma":[0.9993128,0.00009578956,0.0003743477,0.0000455681,0.00008222081,0.00008934522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001316933,0.00009781878,0.9695451,0.0001712308,0.0001752977,0.0004985573,0.0001848008,0.00007985609,0.01271368,0.00005540318,0.0004438564,0.01471751],"study_design_scores_gemma":[0.00001303347,0.0001898838,0.9967705,0.00003682789,0.0000949537,0.0009806713,0.0002304645,0.000143675,0.0007078866,0.00005844596,0.0007677,0.000005939509],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995249,0.002863954,0.0002925712,0.0001055795,0.00002113098,0.000009320017,0.0003811327,0.00002417212,0.001053369],"genre_scores_gemma":[0.9986511,0.000301285,0.0001624468,0.00006822461,0.00002063102,0.000007275431,0.0001782099,0.000005723119,0.0006052663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00493354,"threshold_uncertainty_score":0.01650435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008510627856618493,"score_gpt":0.2036722520394146,"score_spread":0.1951616241827961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}