{"id":"W3203222542","doi":"10.1080/15548627.2021.1972403","title":"Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University; Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Autophagy; Glutaminolysis; Cell biology; Human immunodeficiency virus (HIV); Production (economics); Virology; Genetics; Biochemistry; Metabolism; Apoptosis; Glycolysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404419,0.000205998,0.0002970335,0.0001345353,0.0001397068,0.000393691,0.0001696963,0.0002267818,0.0006833086],"category_scores_gemma":[0.0001211949,0.000106056,0.0001688603,0.000141211,0.000168766,0.0001525845,0.0002030346,0.0006167197,0.0002197601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002083997,"about_ca_system_score_gemma":0.0001397538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002474159,"about_ca_topic_score_gemma":0.0004322973,"domain_scores_codex":[0.9998221,0.00002909026,0.00002777406,0.00004484898,0.00002738433,0.00004881189],"domain_scores_gemma":[0.999894,0.00002555056,0.00002230563,0.00001801668,0.00001124082,0.00002892098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403976,0.00003501112,0.0001799164,0.00002299043,0.000002874178,0.0000278228,0.00001382515,0.00007828739,0.9985048,0.00003865603,0.0000306646,0.0009247842],"study_design_scores_gemma":[0.00003453567,0.0003857547,0.004371121,0.00000474243,0.00001648432,0.0001447338,0.00002466144,0.001449137,0.9923332,0.00005146182,0.00117943,0.000004790686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997777,0.000428069,0.0007641329,0.0000482509,0.00001611023,0.00001908155,0.0002198227,0.00004030145,0.0006872086],"genre_scores_gemma":[0.9970203,0.0001812001,0.001295851,0.00005737867,0.00001012344,0.00003161145,0.0003304252,0.00001230544,0.001060805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006833086,"threshold_uncertainty_score":0.002285898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353097128226494,"score_gpt":0.252488907446616,"score_spread":0.2389579361643511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}