{"id":"W3203497910","doi":"10.1002/mnfr.202100191","title":"Dietary Exposure to the Food Contaminant Deoxynivalenol Triggers Colonic Breakdown by Activating the Mitochondrial and the Death Receptor Pathways","year":2021,"lang":"en","type":"article","venue":"Molecular Nutrition & Food Research","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Agence Nationale de la Recherche","keywords":"Apoptosis; Intestinal permeability; Tumor necrosis factor alpha; Downregulation and upregulation; Myeloperoxidase; Inflammation; Inflammatory bowel disease; Occludin; Biology; Tight junction; Immunology; Internal medicine; Medicine; Cell biology; Biochemistry; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009828695,0.0002462892,0.0001696311,0.0001493771,0.0001086481,0.0002462535,0.00008393879,0.0002818467,0.002322128],"category_scores_gemma":[0.0001235364,0.00006649352,0.0001642196,0.0001374639,0.0001268302,0.0001681487,0.000204816,0.0002238234,0.0003265983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002390107,"about_ca_system_score_gemma":0.0001476474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002100769,"about_ca_topic_score_gemma":0.0003377475,"domain_scores_codex":[0.9998935,0.00001832324,0.000007193082,0.00002532702,0.00002540809,0.00003027607],"domain_scores_gemma":[0.9998951,0.00001145742,0.00005204626,0.000008351276,0.00001585888,0.00001716919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008064453,0.00004554563,0.001999899,0.0002212057,0.0000130302,0.0002985206,0.00003234107,0.00003766127,0.9916672,0.00009448053,0.00008256172,0.004701139],"study_design_scores_gemma":[0.00005274282,0.002304744,0.07773914,0.0001025557,0.00005974265,0.002857675,0.0003445019,0.0005840718,0.9069135,0.0004119323,0.00861702,0.00001238213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875497,0.008274781,0.001672459,0.0002024359,0.00004536652,0.00002068655,0.0004012759,0.00005187797,0.001781447],"genre_scores_gemma":[0.9940565,0.002932146,0.0008421788,0.00008111834,0.00001038484,0.0000163891,0.0002350012,0.00000446528,0.001821818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002322128,"threshold_uncertainty_score":0.007768333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04315866001835528,"score_gpt":0.2608653564713089,"score_spread":0.2177066964529536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}