{"id":"W3203514415","doi":"10.3389/fnhum.2021.739754","title":"Reported Hearing Loss in Alzheimer’s Disease Is Associated With Loss of Brainstem and Cerebellar Volume","year":2021,"lang":"en","type":"article","venue":"Frontiers in Human Neuroscience","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; School of Medicine, Johns Hopkins University; Medical School, University of Michigan; University of California, San Diego; National Institute on Aging; Weill Cornell Medical College; National Institutes of Health; H. Lundbeck A/S; Eisai; Northern California Institute for Research and Education; Genentech; University of South Florida; Ohio State University; Rush University; York University; Pfizer; Northwestern University; Biogen; BioClinica; University of Rochester; IXICO; University of Pittsburgh; University of Texas Southwestern Medical Center; Johns Hopkins University; F. Hoffmann-La Roche; University of Pennsylvania; University of Southern California; Alzheimer's Association; Jewish General Hospital; NYU Langone Medical Center; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Servier; Wake Forest University; University of California, Irvine; Foundation for the National Institutes of Health; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Presbycusis; Hearing loss; Brainstem; Audiology; Context (archaeology); Cerebellum; Psychology; Atrophy; Neuroscience; Alzheimer's disease; Medicine; Disease; Pathology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005876721,0.0003018389,0.0003183523,0.001631726,0.0002244384,0.0007032325,0.0002562455,0.0002771663,0.001833492],"category_scores_gemma":[0.003596589,0.0001838677,0.000296901,0.001098727,0.0003322968,0.0003815703,0.0005818999,0.0003681603,0.0002248868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001912294,"about_ca_system_score_gemma":0.000129431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003355441,"about_ca_topic_score_gemma":0.005900691,"domain_scores_codex":[0.9994536,0.00007628673,0.0000897565,0.0001936041,0.0001439369,0.00004287189],"domain_scores_gemma":[0.9966053,0.0006297978,0.00216219,0.0002466904,0.0001961643,0.000159863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002191754,0.00003124758,0.9870781,0.00005193564,0.0002562554,0.0003012642,0.0001267385,0.0001052466,0.003109498,0.00005071519,0.0002372072,0.008432685],"study_design_scores_gemma":[0.000001091144,0.00001622665,0.9991201,0.000003796238,0.00002314605,0.0004810071,0.00002656899,0.00005845053,0.0001428629,0.00004987143,0.00007493889,0.00000204352],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974891,0.0007514516,0.0003124297,0.00005338257,0.000008278543,0.000004345229,0.0007745762,0.00002433956,0.0005820122],"genre_scores_gemma":[0.998733,0.0002666963,0.0002020935,0.00001376748,0.00001313977,0.000003135798,0.000615207,0.000003768412,0.0001491364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003355441,"threshold_uncertainty_score":0.006671846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05505363247566673,"score_gpt":0.2822886273097303,"score_spread":0.2272349948340636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}