{"id":"W3203514415","doi":"10.3389/fnhum.2021.739754","title":"Reported Hearing Loss in Alzheimer’s Disease Is Associated With Loss of Brainstem and Cerebellar Volume","year":2021,"lang":"en","type":"article","venue":"Frontiers in Human Neuroscience","topic":"Hearing, Cochlea, Tinnitus, Genetics","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; School of Medicine, Johns Hopkins University; Medical School, University of Michigan; University of California, San Diego; National Institute on Aging; Weill Cornell Medical College; National Institutes of Health; H. Lundbeck A/S; Eisai; Northern California Institute for Research and Education; Genentech; University of South Florida; Ohio State University; Rush University; York University; Pfizer; Northwestern University; Biogen; BioClinica; University of Rochester; IXICO; University of Pittsburgh; University of Texas Southwestern Medical Center; Johns Hopkins University; F. Hoffmann-La Roche; University of Pennsylvania; University of Southern California; Alzheimer's Association; Jewish General Hospital; NYU Langone Medical Center; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Servier; Wake Forest University; University of California, Irvine; Foundation for the National Institutes of Health; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Presbycusis; Hearing loss; Brainstem; Audiology; Context (archaeology); Cerebellum; Psychology; Atrophy; Neuroscience; Alzheimer's disease; Medicine; Disease; Pathology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005134578,0.000272766,0.0004512848,0.0003437651,0.000230407,0.0001246563,0.0004983869,0.00009434135,0.00001120146],"category_scores_gemma":[0.002046663,0.0002986011,0.00005228659,0.001812281,0.001083772,0.0003089449,0.0003703096,0.0004189916,6.773334e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008624056,"about_ca_system_score_gemma":0.0003375741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005076059,"about_ca_topic_score_gemma":0.00006287199,"domain_scores_codex":[0.9962283,0.0003267198,0.0006745328,0.001296743,0.0007707285,0.0007029841],"domain_scores_gemma":[0.998455,0.00008299937,0.0003297259,0.0007520184,0.00009300615,0.000287214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003473485,0.0002192623,0.945363,0.00003586004,0.000003725577,0.00265416,0.0008154319,0.001260274,0.04893464,0.00007672507,0.0003334481,0.0002687169],"study_design_scores_gemma":[0.001314847,0.0001664487,0.906311,0.0003101691,0.00003918124,0.0001167428,0.0001525037,0.02172921,0.06786539,0.0004479564,0.0009767162,0.0005698839],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975326,0.0002632741,0.0006562102,0.0003398379,0.0004612775,0.0003379825,0.00002350527,0.00005466129,0.0003306738],"genre_scores_gemma":[0.9978049,0.00009103002,0.0003563869,0.00110441,0.00001651384,0.00001048622,0.000002243486,0.00004087238,0.0005731308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03905207,"threshold_uncertainty_score":0.9999466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05505363247566673,"score_gpt":0.2822886273097303,"score_spread":0.2272349948340636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}