{"id":"W3203546934","doi":"10.1111/all.15130","title":"No apparent impact of incremental dosing on eliciting dose at double‐blind, placebo‐controlled peanut challenge","year":2021,"lang":"en","type":"letter","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Horizon 2020 Framework Programme; Food Standards Agency; Medical Research Council; National Institute for Health and Care Research","keywords":"Dosing; Placebo; Medicine; Double blind; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004910413,0.0008316542,0.001927847,0.0006571764,0.0002413937,0.00006499343,0.0004213731,0.0009844728,0.003968657],"category_scores_gemma":[0.0001820062,0.0006633326,0.001480362,0.0003142406,0.0001706804,0.00008118199,0.0004469345,0.002594545,0.0002356563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008222059,"about_ca_system_score_gemma":0.0005271567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007350506,"about_ca_topic_score_gemma":0.0002405415,"domain_scores_codex":[0.9947959,0.0003145685,0.001033867,0.001016182,0.001690094,0.001149386],"domain_scores_gemma":[0.9972944,0.000460159,0.0005283211,0.0009803605,0.0004376129,0.0002990931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1263773,0.001317359,0.00005237571,0.001315169,0.01359327,0.00490836,0.0004986826,0.0001720022,0.009258898,0.00007584358,0.8388474,0.003583301],"study_design_scores_gemma":[0.170855,0.007487111,0.0002439606,0.003882273,0.00014638,0.0002007312,0.0001741353,0.0006653428,0.002396701,0.00002201138,0.8124973,0.00142906],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4573995,0.01095283,0.000005610384,0.1898275,0.001539485,0.004761771,0.0002165548,0.0002864194,0.3350104],"genre_scores_gemma":[0.8476926,0.005598351,0.0001490167,0.08662323,0.01583619,0.0005387518,0.007713089,0.0005024938,0.03534628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3902931,"threshold_uncertainty_score":0.9997065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06216520764479397,"score_gpt":0.340985705302694,"score_spread":0.2788204976579001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}