{"id":"W3203546934","doi":"10.1111/all.15130","title":"No apparent impact of incremental dosing on eliciting dose at double‐blind, placebo‐controlled peanut challenge","year":2021,"lang":"en","type":"letter","venue":"Allergy","topic":"Food Allergy and Anaphylaxis Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Horizon 2020 Framework Programme; Food Standards Agency; Medical Research Council; National Institute for Health and Care Research","keywords":"Dosing; Placebo; Medicine; Double blind; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007466563,0.001503622,0.003937887,0.0003253133,0.0004204447,0.00129132,0.001344013,0.002187839,0.009652906],"category_scores_gemma":[0.01443867,0.0007898957,0.0007983274,0.0003451655,0.00121033,0.001346528,0.0008957309,0.003707408,0.001887104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005267519,"about_ca_system_score_gemma":0.001082788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005354094,"about_ca_topic_score_gemma":0.0008713125,"domain_scores_codex":[0.9939445,0.002410308,0.0006594312,0.001200492,0.001281123,0.0005042758],"domain_scores_gemma":[0.9914465,0.003887684,0.001348465,0.001683703,0.0007501361,0.0008835013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8480172,0.02453096,0.001254338,0.001847661,0.0005234288,0.00006191558,0.0002995634,0.0006339889,0.07327417,0.0003073701,0.00128039,0.04796904],"study_design_scores_gemma":[0.1303849,0.7899397,0.01965981,0.0003266773,0.000988106,0.00009984248,0.0001313211,0.002771037,0.04389676,0.00102773,0.01064022,0.000133973],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644945,0.004517469,0.005565537,0.0004567148,0.002414997,0.01400332,0.001688011,0.0005182258,0.006341357],"genre_scores_gemma":[0.9714193,0.0009849309,0.008801231,0.000943529,0.0005856441,0.01257887,0.0009475792,0.000152625,0.003586236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009652906,"threshold_uncertainty_score":0.03948748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06216520764479397,"score_gpt":0.340985705302694,"score_spread":0.2788204976579001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}