{"id":"W3203609945","doi":"10.1101/2021.10.07.463549","title":"Evolutionary sweeps of subviral parasites and their phage host bring unique parasite variants and disappearance of a phage CRISPR-Cas system","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh; National Institute of Allergy and Infectious Diseases; Global Affairs Canada; Department for International Development; National Institutes of Health; Department for International Development, UK Government; Styrelsen för Internationellt Utvecklingssamarbete; Burroughs Wellcome Fund","keywords":"Vibrio cholerae; CRISPR; Biology; Bacteriophage; Host (biology); Lineage (genetic); Population; Evolutionary biology; Genome; Pandemic; Virology; Genetics; Coronavirus disease 2019 (COVID-19); Gene; Bacteria; Infectious disease (medical specialty); Demography; Sociology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002520211,0.0001789826,0.0002090471,0.0004922731,0.0003757676,0.0007216033,0.0001976888,0.0004455519,0.00241635],"category_scores_gemma":[0.0006129959,0.0001463018,0.0002329663,0.000450607,0.0003318622,0.0003427176,0.0004496413,0.0006209056,0.0005119838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004296891,"about_ca_system_score_gemma":0.0002236657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001686101,"about_ca_topic_score_gemma":0.002186938,"domain_scores_codex":[0.9998005,0.00001682529,0.00001284529,0.00006503195,0.00006480863,0.00003999729],"domain_scores_gemma":[0.9996089,0.00008231329,0.0001305811,0.00006366972,0.00005174845,0.00006280928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002819263,0.00003359656,0.07097346,0.0001666766,0.00005482508,0.00226626,0.0008303306,0.0005823965,0.8992185,0.00122033,0.0009262335,0.0234455],"study_design_scores_gemma":[0.00002065913,0.000390924,0.4656092,0.00007641201,0.00008001726,0.01421414,0.001980987,0.004353207,0.4635241,0.001630626,0.0480137,0.0001061009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907907,0.0008863781,0.003567913,0.0003171292,0.00005004618,0.00001575283,0.001006564,0.0001552333,0.003210244],"genre_scores_gemma":[0.9937916,0.0003225887,0.002471858,0.0001258512,0.00001181999,0.000007503488,0.0007612418,0.0000381193,0.002469355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00241635,"threshold_uncertainty_score":0.008083463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00893477957352134,"score_gpt":0.2314356827444668,"score_spread":0.2225009031709454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}