{"id":"W3203781918","doi":"10.3390/biomedicines9101361","title":"CK2 Regulation: Perspectives in 2021","year":2021,"lang":"en","type":"review","venue":"Biomedicines","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; Kinase; Biology; ASK1; Phosphorylation; Protein kinase A; Casein kinase 2; MAP2K7; Mitogen-activated protein kinase kinase; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006467073,0.0008672341,0.0009877717,0.001349819,0.0003022899,0.001532934,0.0008887892,0.001430554,0.0031639],"category_scores_gemma":[0.0007428139,0.0002445241,0.0004584525,0.001463608,0.0006066282,0.002544996,0.000885956,0.00258482,0.002112359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009088901,"about_ca_system_score_gemma":0.001164194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007894675,"about_ca_topic_score_gemma":0.001438802,"domain_scores_codex":[0.9998112,0.00003343044,0.00002551309,0.00004078715,0.00005596346,0.00003306413],"domain_scores_gemma":[0.9997216,0.0001040486,0.00003289467,0.00001171955,0.00008568653,0.00004410033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002476301,0.00007742656,0.000262852,0.01702856,0.00009101031,0.0006061418,0.0001344959,0.0005499504,0.005365639,0.02115921,0.104646,0.8498311],"study_design_scores_gemma":[0.000008099166,0.00004749139,0.0003416608,0.001438565,0.00003426622,0.0009080174,0.00003472626,0.00005556369,0.0004628367,0.002344936,0.994314,0.000009969196],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001113405,0.9970418,0.00009923441,0.0007141236,0.0008533022,0.000001790298,0.00001357447,0.000005625503,0.001159201],"genre_scores_gemma":[0.0008981102,0.9964264,0.0001122842,0.0006721023,0.0006231026,0.000003769194,0.00003937056,0.000003177414,0.001221603],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0031639,"threshold_uncertainty_score":0.01058429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03972650989910767,"score_gpt":0.3405057968688389,"score_spread":0.3007792869697312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}