{"id":"W3204055340","doi":"10.3389/fonc.2021.671972","title":"Efficacy and Safety of Tumor Treating Fields (TTFields) in Elderly Patients with Newly Diagnosed Glioblastoma: Subgroup Analysis of the Phase 3 EF-14 Clinical Trial","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; University of Ottawa","funders":"Novocure","keywords":"Glioblastoma; Medicine; Subgroup analysis; Oncology; Clinical trial; Internal medicine; Pooled analysis; Phases of clinical research; Meta-analysis; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004235662,0.00109491,0.003094191,0.0005958073,0.0003293859,0.0008030908,0.0005107952,0.0009117454,0.001673465],"category_scores_gemma":[0.003643517,0.0002620794,0.005118999,0.0005868616,0.0003655393,0.0006971598,0.000544867,0.00103273,0.0002047198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006502222,"about_ca_system_score_gemma":0.0009426501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006877548,"about_ca_topic_score_gemma":0.002224875,"domain_scores_codex":[0.998408,0.0008144953,0.0002721454,0.0002217026,0.0001082788,0.0001752956],"domain_scores_gemma":[0.99848,0.0004765714,0.0004532865,0.0002315583,0.0001179116,0.0002405867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9299187,0.001435263,0.02588719,0.0006274607,0.01446278,0.0001327403,0.0001043506,0.0009146401,0.002977628,0.0001129303,0.001019265,0.02240692],"study_design_scores_gemma":[0.6256105,0.1392713,0.1742617,0.0002618113,0.04602302,0.00053176,0.0003321953,0.004611224,0.002398893,0.00195162,0.004578513,0.0001674238],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990799,0.005745325,0.0004044477,0.0002689318,0.0001381237,0.000925081,0.001062069,0.00002804643,0.0006291476],"genre_scores_gemma":[0.9954347,0.0008729405,0.0003947664,0.0004193595,0.0001591742,0.001122112,0.001239081,0.00001143901,0.0003463852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004235662,"threshold_uncertainty_score":0.02240056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01580905253479396,"score_gpt":0.3275255600278723,"score_spread":0.3117165074930783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}