{"id":"W3204249614","doi":"10.1080/01635581.2021.1981404","title":"Genetic Interpretation of the Impacts of Honokiol and EGCG on Apoptotic and Self-Renewal Pathways in HEp-2 Human Laryngeal CD44<sup>high</sup> Cancer Stem Cells","year":2021,"lang":"en","type":"article","venue":"Nutrition and Cancer","topic":"Magnolia and Illicium research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cancer research; CD44; Cancer stem cell; Radioresistance; Apoptosis; Biology; Carcinogenesis; Honokiol; Wnt signaling pathway; Stem cell; Cancer; Cancer cell; Programmed cell death; Signal transduction; Cell culture; Cell; Cell biology; Pharmacology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008190698,0.0002044662,0.0001395623,0.0001924048,0.00008856569,0.000147671,0.0001309462,0.0001759565,0.0008519783],"category_scores_gemma":[0.00005619697,0.00007519541,0.0002381806,0.0001711413,0.0001722277,0.0001349933,0.00009628788,0.0002976805,0.0001497992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002492054,"about_ca_system_score_gemma":0.0001624037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001122372,"about_ca_topic_score_gemma":0.001453178,"domain_scores_codex":[0.9999207,0.00001171315,0.00001219923,0.00001647342,0.00002014067,0.00001878329],"domain_scores_gemma":[0.9999455,0.00001207593,0.00001209383,0.00001045649,0.000009208717,0.00001076355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001228644,0.00001837612,0.0002487962,0.00001873437,0.000003789303,0.00003413848,0.00001577347,0.00005583005,0.9987395,0.00008086927,0.000008589541,0.0006527805],"study_design_scores_gemma":[0.000006349424,0.0001918678,0.005027011,0.000001612481,0.00001504674,0.00006390285,0.00002851697,0.0003550999,0.9935819,0.00002522859,0.0007015535,0.000001872676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969949,0.0004975083,0.001203068,0.00003395191,0.00001065783,0.00002158531,0.0004007541,0.00003030154,0.0008073212],"genre_scores_gemma":[0.9956975,0.000425061,0.001316272,0.00002806571,0.000002468328,0.0000424922,0.0005393042,0.000009499519,0.001939244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122372,"threshold_uncertainty_score":0.002850175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01758523977120537,"score_gpt":0.288722341871905,"score_spread":0.2711371021006997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}