{"id":"W3204288709","doi":"10.1016/j.annonc.2021.08.1435","title":"1050P Outcome and impact of immune related adverse events in patients with advanced melanoma treated with checkpoint inhibitors","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Francis Xavier University; BC Cancer Agency","funders":"","keywords":"Medicine; Adverse effect; Melanoma; Oncology; Immune checkpoint; Internal medicine; Immune system; Immunotherapy; Immunology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003907342,0.0001778704,0.0002729199,0.0002818486,0.000241087,0.0006197467,0.0001989931,0.0003069078,0.001578222],"category_scores_gemma":[0.001452697,0.000102222,0.0006176911,0.000441058,0.0001521139,0.0004186624,0.0003096959,0.0006824154,0.0001861599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004334241,"about_ca_system_score_gemma":0.000263163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001409679,"about_ca_topic_score_gemma":0.002337151,"domain_scores_codex":[0.999733,0.0000733683,0.00002317952,0.00004374854,0.00005075801,0.0000759891],"domain_scores_gemma":[0.9991924,0.0001674199,0.0003685826,0.00002845667,0.00007389043,0.000169357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003806202,0.0001742125,0.9798546,0.00004671128,0.0004753492,0.0002557367,0.00003231599,0.0005396096,0.0006714496,0.00007941568,0.0005888183,0.01347547],"study_design_scores_gemma":[0.00007904964,0.0008130439,0.9972403,0.00001360602,0.0002251241,0.0003267087,0.00005676156,0.0004916643,0.0001209835,0.000132214,0.0004941659,0.000006419148],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959752,0.001251636,0.00007270133,0.0002138199,0.00003601823,0.000007898171,0.0004871387,0.000004305823,0.001951337],"genre_scores_gemma":[0.9988335,0.0002210632,0.00002608188,0.00007989759,0.00004204176,0.000005061442,0.0004368203,0.00000149548,0.0003539757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001578222,"threshold_uncertainty_score":0.00527966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02104005985972968,"score_gpt":0.3314567446937864,"score_spread":0.3104166848340567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}