{"id":"W3204325537","doi":"10.1158/1535-7163.mct-21-0368","title":"IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer","year":2021,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"NorQuest College","funders":"National Institute for Occupational Safety and Health; National Institute of Environmental Health Sciences; National Cancer Institute; National Institutes of Health","keywords":"Pancreatic cancer; Medicine; Immunoglobulin E; Immunotherapy; Cancer research; Ovalbumin; Immunology; Cancer; Cancer immunotherapy; Antigen; Antibody; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002876329,0.0005380625,0.0006029546,0.0004360855,0.0001364756,0.0002842983,0.0003383324,0.0004664724,0.001263126],"category_scores_gemma":[0.0001378371,0.0001678407,0.0003475919,0.0002631485,0.0001924989,0.0002578036,0.0001952449,0.001941416,0.0002552343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002743879,"about_ca_system_score_gemma":0.0003386204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005177122,"about_ca_topic_score_gemma":0.001154587,"domain_scores_codex":[0.9997883,0.00004161815,0.00001917544,0.00003134252,0.00005149581,0.00006802402],"domain_scores_gemma":[0.9999102,0.00001281052,0.00002078701,0.00001038004,0.000009655522,0.00003616009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001681926,0.003727112,0.000254031,0.000219156,0.00004808042,0.0001012039,0.00005057006,0.001059781,0.9796665,0.0001847377,0.0007054966,0.0123014],"study_design_scores_gemma":[0.0008442947,0.03742036,0.005595783,0.00003887594,0.0001663995,0.0003892219,0.00006179092,0.004525886,0.9440539,0.0002152805,0.006666998,0.00002114713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903881,0.002791431,0.002088522,0.0003555702,0.0001817569,0.0002187036,0.0006097894,0.0003025323,0.003063656],"genre_scores_gemma":[0.9926786,0.001977619,0.001447781,0.0002101538,0.00006026264,0.0002342176,0.0008230704,0.00002322494,0.002545103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263126,"threshold_uncertainty_score":0.004225552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04312509767328399,"score_gpt":0.3266197887092266,"score_spread":0.2834946910359426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}