{"id":"W3204408447","doi":"10.1136/medethics-2021-107720","title":"Heritable human genome editing is ‘currently not permitted’, but it is no longer ‘prohibited’: so says the ISSCR","year":2021,"lang":"en","type":"article","venue":"Journal of Medical Ethics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Subject (documents); Law; Research ethics; Political science; Psychology; Computer science; Library science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01578498,0.0005480367,0.0008245242,0.0004570026,0.00348564,0.006759688,0.001862428,0.01750568,0.009919817],"category_scores_gemma":[0.03928808,0.0005607217,0.001314564,0.0006220713,0.0123334,0.005846706,0.003328441,0.02501366,0.007220933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002606329,"about_ca_system_score_gemma":0.01278715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01241322,"about_ca_topic_score_gemma":0.01970808,"domain_scores_codex":[0.9823174,0.003235695,0.001731216,0.002641105,0.008732392,0.001342202],"domain_scores_gemma":[0.9632011,0.02215789,0.001973205,0.003339197,0.006749775,0.002578809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003271231,0.00003390252,0.0004082471,0.0001794061,0.00001249559,0.0001468695,0.001188849,0.00006033187,0.001104843,0.1151367,0.8512567,0.03043895],"study_design_scores_gemma":[0.000009381136,0.00001950014,0.0003671254,0.0001512803,0.00001046198,0.0001810322,0.0002371773,0.0000374394,0.0008586165,0.01332012,0.9847793,0.00002860475],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001250079,0.005238765,0.004754764,0.889992,0.03819176,0.00002895714,0.0002670682,0.0003770668,0.05989957],"genre_scores_gemma":[0.01526403,0.003439036,0.004820103,0.896428,0.006161693,0.00009373828,0.0003493296,0.0003040001,0.07314],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.9824943,"threshold_uncertainty_score":0.08347994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03088127317579206,"score_gpt":0.3724336461460304,"score_spread":0.3415523729702383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}