{"id":"W3204466718","doi":"10.1016/j.euroneuro.2021.07.085","title":"GENES TO MENTAL HEALTH (G2MH), HARNESSING RARE DISEASE TO UNDERSTAND HOW THE COMBINED EFFECTS OF RARE AND COMMON VARIATION SHAPE PSYCHIATRIC TRAITS/CLINICAL DIAGNOSIS","year":2021,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Biotechnology and Related Fields","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Université de Montréal","funders":"","keywords":"Humanities; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003645684,0.0002192434,0.0004484772,0.0001532882,0.0002452572,0.00002579645,0.0001912959,0.0002564468,0.00004768119],"category_scores_gemma":[0.000188802,0.0001701101,0.0001189941,0.0005991898,0.0001708511,0.00004255069,0.0001745384,0.001155912,0.00001449483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002615472,"about_ca_system_score_gemma":0.0001076367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002224766,"about_ca_topic_score_gemma":0.00000332277,"domain_scores_codex":[0.9970905,0.001453828,0.0004465266,0.0005441625,0.0001573509,0.0003076651],"domain_scores_gemma":[0.9986458,0.0003711807,0.0001760546,0.0003039491,0.00006871651,0.0004343092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0122689,0.005620041,0.06639074,0.00209819,0.001461268,0.004487347,0.00663649,0.00006336928,0.258182,0.001358402,0.2476656,0.3937677],"study_design_scores_gemma":[0.006886374,0.002159751,0.9645416,0.0001800365,0.0003490468,0.0001199971,0.0001919426,0.0001565945,0.0006686478,0.00002961766,0.02449966,0.0002167624],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7248176,0.003129632,0.0001961528,0.269,0.001660888,0.0009455312,0.00001681203,0.0001103767,0.0001230055],"genre_scores_gemma":[0.9579988,0.00425395,0.0003071448,0.03692656,0.0002367932,0.0000172983,0.00001732302,0.00006292437,0.0001792597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8981508,"threshold_uncertainty_score":0.6936889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02260867284619062,"score_gpt":0.3190498413135804,"score_spread":0.2964411684673898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}