{"id":"W3204782972","doi":"10.30683/1927-7229.2021.10.01","title":"Tryptophan Metabolism and Cancer Progression","year":2021,"lang":"en","type":"article","venue":"Journal of Analytical Oncology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Science and Technology, Taiwan","keywords":"Melatonin; Kynurenine; Cancer cell; Cancer; Aryl hydrocarbon receptor; Metastasis; Biology; Cancer research; Receptor; Cell growth; Kynurenine pathway; Signal transduction; Chemistry; Tryptophan; Biochemistry; Endocrinology; Transcription factor; Amino acid","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676804,0.0001984196,0.0001600063,0.0005328166,0.0002101993,0.000605436,0.0001360279,0.0002957864,0.003569795],"category_scores_gemma":[0.0003348336,0.00005471133,0.0001717632,0.0004659769,0.0001145873,0.0001672646,0.0002465479,0.0003285063,0.0005721775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005066483,"about_ca_system_score_gemma":0.0004188871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002945089,"about_ca_topic_score_gemma":0.001981441,"domain_scores_codex":[0.99992,0.00002298103,0.000007006453,0.00001559659,0.00001539296,0.00001896906],"domain_scores_gemma":[0.9998676,0.00001522674,0.0000539425,0.000005611195,0.0000301115,0.00002745843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003768762,0.0007821111,0.2457115,0.002330443,0.000828406,0.004629564,0.0006230208,0.001227077,0.1568832,0.009130613,0.02627462,0.5478107],"study_design_scores_gemma":[0.0001988671,0.001466111,0.7256296,0.000620146,0.0005591263,0.009761143,0.0006152423,0.002282452,0.04640104,0.007484221,0.2049355,0.00004654736],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6141374,0.3546172,0.002923723,0.003840363,0.0003777318,0.0001000281,0.002824894,0.0002245297,0.02095419],"genre_scores_gemma":[0.9411401,0.04593307,0.0006646198,0.0002913238,0.0001143917,0.00005120433,0.001264435,0.00001620251,0.01052466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003569795,"threshold_uncertainty_score":0.01194209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03892142062479351,"score_gpt":0.3698454870265169,"score_spread":0.3309240664017233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}