{"id":"W3204843825","doi":"10.1016/j.annonc.2021.08.517","title":"234P Effect of palbociclib (PAL) + endocrine therapy (ET) on time to chemotherapy (TTC) across subgroups of patients (pts) with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC): Post hoc analyses from PALOMA-2 (P2) and PALOMA-3 (P3)","year":2021,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Palbociclib; Internal medicine; Human Epidermal Growth Factor Receptor 2; Chemotherapy; Oncology; Endocrine system; Chemotherapy regimen; Endocrinology; Hormone receptor; Receptor; Hormone; Cancer; Metastatic breast cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001373763,0.0005965218,0.001415356,0.0002775757,0.0002165149,0.000770516,0.0005821172,0.0006718756,0.01006414],"category_scores_gemma":[0.00260925,0.0002127877,0.002727527,0.0002959588,0.0003618433,0.00100941,0.000511303,0.002300071,0.0004156709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004871462,"about_ca_system_score_gemma":0.001091768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003192195,"about_ca_topic_score_gemma":0.004359219,"domain_scores_codex":[0.9990928,0.0003647916,0.00004491297,0.0001529537,0.00006598072,0.0002786143],"domain_scores_gemma":[0.9973865,0.001712377,0.0001969318,0.0001247312,0.0000736818,0.0005057683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8457233,0.003506487,0.08536455,0.0002570924,0.005190816,0.00040164,0.0002056316,0.00220567,0.009094601,0.0002659016,0.003130728,0.04465351],"study_design_scores_gemma":[0.02224686,0.2103311,0.7325268,0.00009327097,0.007630497,0.000552734,0.001134672,0.0109854,0.006601882,0.00105356,0.006745405,0.00009783433],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968483,0.0004401441,0.0001658674,0.0001710562,0.00007598664,0.00003634326,0.0008977196,0.0000142179,0.001350461],"genre_scores_gemma":[0.9962411,0.0001554219,0.0001325183,0.0001520219,0.00005453356,0.00006677266,0.0008132594,0.000009852312,0.00237449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01006414,"threshold_uncertainty_score":0.03366786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02605334179475607,"score_gpt":0.3776716080813189,"score_spread":0.3516182662865628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}