{"id":"W3204875813","doi":"10.3390/biomedicines9101348","title":"ReCODE: A Personalized, Targeted, Multi-Factorial Therapeutic Program for Reversal of Cognitive Decline","year":2021,"lang":"en","type":"article","venue":"Biomedicines","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Montreal Cognitive Assessment; Cognition; Medicine; Cognitive decline; Wilcoxon signed-rank test; Randomized controlled trial; Clinical trial; Cognitive impairment; Disease; Gerontology; Psychiatry; Dementia; Internal medicine; Mann–Whitney U test","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003724027,0.0001830366,0.0004481456,0.0001612946,0.00006466729,0.00001456867,0.00007500123,0.000110187,0.0006534159],"category_scores_gemma":[0.0009765703,0.0001386702,0.0002114211,0.0004587232,0.0003444207,0.00005406655,0.00005667321,0.0001258968,0.00001243811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003421688,"about_ca_system_score_gemma":0.0004100629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002831819,"about_ca_topic_score_gemma":0.00001316251,"domain_scores_codex":[0.9983204,0.00007853096,0.0003573398,0.0003538617,0.0005196189,0.0003702223],"domain_scores_gemma":[0.9979512,0.0003584747,0.0001061442,0.0001504452,0.001250144,0.0001836079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.009306501,0.006894613,0.2957671,0.001694939,0.002205079,0.0003072868,0.001803378,3.40769e-8,0.2386052,0.0001896482,0.005094985,0.4381313],"study_design_scores_gemma":[0.09394877,0.01617472,0.4388152,0.002681262,0.003136004,0.0003194688,0.009042887,0.001000108,0.1890783,0.0006333002,0.2443318,0.0008381546],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9525957,0.008851744,0.0231679,0.005687068,0.002082054,0.005575707,0.0004028497,0.0002219143,0.001415035],"genre_scores_gemma":[0.9849908,0.0003629981,0.006784286,0.000752741,0.001048831,0.0003807486,0.0008131742,0.00003837155,0.004828102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4372931,"threshold_uncertainty_score":0.7154446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05059287528007087,"score_gpt":0.3960953303012519,"score_spread":0.345502455021181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}