{"id":"W3204918577","doi":"10.1128/jb.00458-21","title":"Heme-Dependent Siderophore Utilization Promotes Iron-Restricted Growth of the Staphylococcus aureus <i>hemB</i> Small-Colony Variant","year":2021,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Siderophore; Hemin; Staphylococcus aureus; Microbiology; Biology; Bacteria; Mutant; Heme; Intracellular; Biochemistry; Gene; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007841882,0.0001686722,0.0001464049,0.0001023902,0.00009595846,0.0002465051,0.0002392045,0.0001704809,0.001029286],"category_scores_gemma":[0.0002068835,0.00006992683,0.0001311682,0.00008777703,0.0001337942,0.0000795231,0.0002074,0.0004342967,0.0003210513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002128346,"about_ca_system_score_gemma":0.0002024075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003124348,"about_ca_topic_score_gemma":0.002819623,"domain_scores_codex":[0.9998859,0.00001937031,0.00001049125,0.00001842112,0.00003948412,0.00002636827],"domain_scores_gemma":[0.9998642,0.00002627493,0.00003141603,0.00001989278,0.00001560199,0.00004256995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006305751,0.00003328902,0.0002435531,0.000007631907,0.000002440905,0.00005883248,0.00001676063,0.00004662997,0.9987626,0.00009775773,0.00008002987,0.0005872124],"study_design_scores_gemma":[0.00001923571,0.0006750861,0.01322947,0.00001077383,0.000007909717,0.0005841912,0.0001413301,0.003016327,0.9796281,0.00007626897,0.002600109,0.00001110381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981403,0.00009472072,0.0006326548,0.00005884867,0.000009172662,0.00001032523,0.0001859877,0.00002530304,0.0008426576],"genre_scores_gemma":[0.9973748,0.00004644809,0.0008571961,0.00002719179,0.000003146156,0.00001102061,0.0003795327,0.00002809883,0.001272687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003124348,"threshold_uncertainty_score":0.006212354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02570067753681052,"score_gpt":0.2641835882352906,"score_spread":0.2384829106984801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}