{"id":"W3205094601","doi":"10.1039/d1tb01864g","title":"Antibacterial activities of physiologically stable, self-assembled peptide nanoparticles","year":2021,"lang":"en","type":"article","venue":"Journal of Materials Chemistry B","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Prince Edward Island","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Canadian Poultry Research Council","keywords":"Peptide; Biophysics; Fucoidan; Nanogel; Antibacterial peptide; Nanoparticle; Nanocarriers; Biology; Bacteria; Chemistry; Nanotechnology; Materials science; Biochemistry; Polysaccharide; Antibacterial activity; Drug delivery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211958,0.0001632689,0.0004347079,0.00001419557,0.00004002367,0.00004992831,0.0002031828,0.0001478057,0.0002255299],"category_scores_gemma":[0.0001507672,0.000129894,0.0001692115,0.00005927877,0.00004160556,0.0000150529,0.0001332055,0.0000673278,0.000001112786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001650418,"about_ca_system_score_gemma":0.0001922888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002706701,"about_ca_topic_score_gemma":6.21816e-7,"domain_scores_codex":[0.9987663,0.0001080556,0.0005506749,0.000188267,0.0001892424,0.0001974386],"domain_scores_gemma":[0.998748,0.00002051766,0.0006373544,0.0002226634,0.0002993305,0.00007215004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004896747,0.0002577748,0.0001954408,0.0001309289,0.0002215518,0.00002417736,0.00001912939,0.000009466288,0.9983508,0.000004044817,0.000223159,0.00007387666],"study_design_scores_gemma":[0.0006144612,0.0001843097,0.001289866,0.00006003735,0.00005664646,0.0001189874,0.00009928523,5.707731e-7,0.9959756,0.00005315579,0.001402654,0.0001444011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999126,0.0002928696,0.00001873851,0.00005078154,0.000152799,0.00004346479,0.0000317769,0.000005438731,0.0002781501],"genre_scores_gemma":[0.9972512,0.0004292188,0.00149918,0.00003117575,0.0006445476,0.000002863729,0.00002041757,0.00001384384,0.0001075897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002375151,"threshold_uncertainty_score":0.5296925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007555334421434492,"score_gpt":0.2266580806553996,"score_spread":0.2191027462339651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}