{"id":"W3205153815","doi":"10.1016/j.htct.2021.10.040","title":"LONG-TERM SAFETY AND EFFICACY OF DEFERIPRONE FOR THE TREATMENT OF CHRONICALLY TRANSFUSED, IRON-OVERLOADED PATIENTS WITH SICKLE CELL DISEASE OR OTHER ANEMIAS","year":2021,"lang":"en","type":"article","venue":"Hematology Transfusion and Cell Therapy","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Deferiprone; Medicine; Neutropenia; Internal medicine; Nausea; Adverse effect; Vomiting; Gastroenterology; Ferritin; Deferasirox; Anemia; Deferoxamine; Surgery; Thalassemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004585538,0.0001983585,0.000495213,0.00002947199,0.00009987204,0.000004203858,0.00004041212,0.0001417163,0.0003007631],"category_scores_gemma":[0.000003233666,0.0001003735,0.0001206369,0.0001025695,0.0002619195,0.00001909569,0.000003499932,0.00007696698,4.931738e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000129541,"about_ca_system_score_gemma":0.0001339776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001828575,"about_ca_topic_score_gemma":0.00004632218,"domain_scores_codex":[0.9990306,0.00005118622,0.0003125659,0.0002882867,0.0001234384,0.0001938591],"domain_scores_gemma":[0.9992648,0.0002182136,0.00007178765,0.0002448037,0.00007043591,0.0001299618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2235202,0.037441,0.4477428,0.005253727,0.001309386,0.0002267759,0.01656581,0.00006722946,0.06083603,0.0004386455,0.0001053401,0.2064931],"study_design_scores_gemma":[0.269469,0.02321239,0.4438285,0.0007113583,0.002445106,0.0001418271,0.001689888,0.0002123583,0.2440834,0.00003547675,0.01333566,0.0008350373],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790629,0.01794892,0.000822662,0.0006098253,0.00003941033,0.00130909,0.00004240543,0.00001396012,0.0001508735],"genre_scores_gemma":[0.9194696,0.0797495,0.0001292287,0.0002056374,0.000008851668,0.00003109891,0.00003686804,0.00002911721,0.0003400823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2056581,"threshold_uncertainty_score":0.4093112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009885080925204846,"score_gpt":0.2382667479952514,"score_spread":0.2283816670700465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}