{"id":"W3205153815","doi":"10.1016/j.htct.2021.10.040","title":"LONG-TERM SAFETY AND EFFICACY OF DEFERIPRONE FOR THE TREATMENT OF CHRONICALLY TRANSFUSED, IRON-OVERLOADED PATIENTS WITH SICKLE CELL DISEASE OR OTHER ANEMIAS","year":2021,"lang":"en","type":"article","venue":"Hematology Transfusion and Cell Therapy","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Deferiprone; Medicine; Neutropenia; Internal medicine; Nausea; Adverse effect; Vomiting; Gastroenterology; Ferritin; Deferasirox; Anemia; Deferoxamine; Surgery; Thalassemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002239392,0.0003453571,0.001056138,0.0002146076,0.0002657406,0.0004539882,0.0002909173,0.0007666642,0.0006561039],"category_scores_gemma":[0.002619259,0.0001398038,0.0007634298,0.0001757519,0.00031351,0.0003896681,0.0001912766,0.0009572009,0.0001199218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003950566,"about_ca_system_score_gemma":0.0004591409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003265024,"about_ca_topic_score_gemma":0.0008084587,"domain_scores_codex":[0.9995234,0.0002626232,0.0000506512,0.0000473017,0.00006431681,0.00005168287],"domain_scores_gemma":[0.9972184,0.0008866579,0.001010087,0.0001263884,0.0001501219,0.0006083541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7256175,0.007935096,0.06829018,0.001103333,0.002059473,0.0003633741,0.0002775685,0.001243173,0.01822847,0.0001563829,0.001106937,0.1736185],"study_design_scores_gemma":[0.1681632,0.60211,0.2157437,0.0002681489,0.002205483,0.0009016412,0.0001358997,0.002030354,0.005327994,0.0002038884,0.002833598,0.000076061],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929797,0.006187025,0.0001021887,0.0001417717,0.000026383,0.00006742739,0.0001696969,0.000008063559,0.0003177358],"genre_scores_gemma":[0.9982184,0.001006771,0.0001511504,0.0001268234,0.00007205319,0.00005474909,0.000245812,0.000001058586,0.0001231585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002239392,"threshold_uncertainty_score":0.01184314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009885080925204846,"score_gpt":0.2382667479952514,"score_spread":0.2283816670700465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}