{"id":"W3205381631","doi":"10.1080/2162402x.2021.1984677","title":"Trial watch: intratumoral immunotherapy","year":2021,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Labex Immuno-Oncology; High-end Foreign Experts Recruitment Plan of China; Stand Up To Cancer; Weill Cornell Medical College; European Research Area Network on Cardiovascular Diseases; Institut Universitaire de France; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; Association pour la Recherche sur le Cancer; Seerave Foundation; Institut Gustave-Roussy; Fondation Leducq; European Commission; Agence Nationale de la Recherche; E-Rare; Leukemia and Lymphoma Society","keywords":"Oncolytic virus; Immunotherapy; Immune system; Chemotherapy; Context (archaeology); Radiation therapy; T cell; Cancer immunotherapy; Myeloid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001901066,0.0001807051,0.0004534627,0.00005616305,0.00009068122,0.00002539931,0.0001185054,0.0002192789,0.003025233],"category_scores_gemma":[0.00005135313,0.000158862,0.0002555823,0.000316355,0.0002056143,0.00006187192,0.00004176258,0.0003277101,0.0001538762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001485743,"about_ca_system_score_gemma":0.0005337995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008287039,"about_ca_topic_score_gemma":0.0000228877,"domain_scores_codex":[0.9986664,0.0001138169,0.0003773143,0.000318574,0.0001581502,0.0003657109],"domain_scores_gemma":[0.9991118,0.00005861629,0.00008739859,0.0005703064,0.0001231785,0.0000486448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1815659,0.0008623378,0.0009019213,0.00002446298,0.0008571292,0.0006422754,0.0004982805,2.164961e-7,0.6401304,0.001141808,0.008585354,0.16479],"study_design_scores_gemma":[0.1552578,0.002812119,0.01333307,0.00006374115,0.00007417635,0.001574855,0.0004486028,0.0000049574,0.07005774,0.0004089535,0.755648,0.0003159835],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567018,0.01079192,0.00007980916,0.01106986,0.002299075,0.0003977306,0.000006399263,0.0001473626,0.01850601],"genre_scores_gemma":[0.9681282,0.003430519,0.001174468,0.005026509,0.0005980043,0.00008283361,0.0001161691,0.00005780955,0.02138551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7470626,"threshold_uncertainty_score":0.9978861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02284380497408721,"score_gpt":0.3018789860251105,"score_spread":0.2790351810510233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}