{"id":"W3205391626","doi":"10.1101/2021.07.13.452235","title":"Divergence in dimerization and activity of primate APOBEC3C","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cytidine; Cytidine deaminase; Amino acid; Biology; DNA; Uracil; Dimer; Deamination; Macaque; Biochemistry; Chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002798209,0.0001515388,0.0001688123,0.0002695858,0.0004594764,0.0003829518,0.000276415,0.0003924473,0.001094032],"category_scores_gemma":[0.0003868976,0.00008994664,0.0002430062,0.0002922628,0.000277174,0.0002862809,0.0002295494,0.0006069819,0.0002213431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006711099,"about_ca_system_score_gemma":0.0002181686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004385365,"about_ca_topic_score_gemma":0.003359299,"domain_scores_codex":[0.9998559,0.00002898363,0.000006967756,0.0000484876,0.0000331252,0.00002652481],"domain_scores_gemma":[0.999879,0.00002660175,0.00002239947,0.00001321951,0.00002542633,0.00003336645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004111434,0.00009912431,0.03354819,0.0001094393,0.000135676,0.0002556619,0.0004473205,0.004237195,0.9401672,0.00290759,0.0005376974,0.0171438],"study_design_scores_gemma":[0.0001261835,0.0007546072,0.4853688,0.00008205002,0.0003735487,0.003868955,0.001331741,0.1272501,0.3507478,0.007495189,0.02246091,0.0001400782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977506,0.0004736641,0.0005482959,0.00004168371,0.000004000337,0.000002341369,0.00008523653,0.0000187385,0.001075519],"genre_scores_gemma":[0.9991269,0.00009246838,0.0004029135,0.00002907025,0.000002068506,0.000002577343,0.0001232561,0.000007228819,0.0002135187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004385365,"threshold_uncertainty_score":0.008719683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0135534570770997,"score_gpt":0.2391631171816858,"score_spread":0.2256096601045861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}