{"id":"W3205403261","doi":"10.3389/fphar.2021.750816","title":"Carbon Monoxide in Pancreatic Islet Transplantation: A New Therapeutic Alternative to Patients With Severe Type 1 Diabetes Mellitus","year":2021,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Transplantation; Islet; Medicine; Diabetes mellitus; Pancreas transplantation; Type 2 Diabetes Mellitus; Type 1 diabetes; Hypoglycemia; Insulin; Internal medicine; Endocrinology; Intensive care medicine; Kidney transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000358952,0.0005886511,0.0009922837,0.001255575,0.0001961864,0.0006398293,0.0006254808,0.0009166019,0.002836639],"category_scores_gemma":[0.0004286354,0.0001367604,0.0003831314,0.00108598,0.0003643211,0.0009547071,0.0005266279,0.002158081,0.001354115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000353136,"about_ca_system_score_gemma":0.0005877681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004601436,"about_ca_topic_score_gemma":0.0009510932,"domain_scores_codex":[0.999876,0.00002672989,0.00001620987,0.00002219876,0.00004731022,0.000011555],"domain_scores_gemma":[0.9998569,0.00007205366,0.00001871138,0.000004507617,0.0000310764,0.00001661705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00008857781,0.00007459655,0.0001470566,0.0128621,0.00008540969,0.0002135341,0.00004660144,0.000235091,0.001802194,0.004595039,0.02847458,0.9513751],"study_design_scores_gemma":[0.00002102639,0.0001184529,0.0007190449,0.002915984,0.00008826426,0.001395653,0.0000430103,0.00008489109,0.0004323939,0.002770229,0.9913954,0.00001564234],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008445196,0.9984906,0.0001199613,0.0003210625,0.0003121483,0.000002632426,0.000008289289,0.000005746622,0.0006550921],"genre_scores_gemma":[0.0005880065,0.9983222,0.0001391641,0.0002362,0.0002931781,0.000004304083,0.00001643266,0.000001448901,0.0003990864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002836639,"threshold_uncertainty_score":0.009489536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306982359865347,"score_gpt":0.283329494776279,"score_spread":0.2702596711776255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}