{"id":"W3205415979","doi":"10.1200/jco.21.00358","title":"Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Izaak Walton Killam Health Centre","funders":"National Cancer Institute","keywords":"Chemotherapy; Clinical trial; Phases of clinical research; Overall survival; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001808736,0.0002757645,0.002717684,0.0001433771,0.0001049205,0.00001325689,0.0001587406,0.0002490786,0.0002258492],"category_scores_gemma":[0.003601026,0.0001523988,0.0007861455,0.0003122968,0.0001999403,0.00007695422,0.00008039931,0.0005057539,0.000009032025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006091305,"about_ca_system_score_gemma":0.002495457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009940327,"about_ca_topic_score_gemma":0.000142365,"domain_scores_codex":[0.994205,0.0007641229,0.00364346,0.0003812293,0.0006402677,0.0003659506],"domain_scores_gemma":[0.9912674,0.00422446,0.002860725,0.0004435131,0.0006958028,0.0005080366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1870158,0.08638982,0.1662985,0.00001938901,0.003681878,0.02582379,0.0004262656,0.00001265911,0.00002405958,0.00004800937,0.00156287,0.528697],"study_design_scores_gemma":[0.4319362,0.1845077,0.3170325,0.0001859823,0.003824196,0.00289136,0.0002533463,0.000008555219,0.0003161449,0.00004533811,0.0588131,0.0001855279],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908251,0.0006342038,0.0002177591,0.005026396,0.001481635,0.00107873,0.00003270924,0.000008826085,0.0006946619],"genre_scores_gemma":[0.9876954,0.0003079979,0.008953359,0.001315805,0.001518829,0.00005656884,0.00006913928,0.00003071826,0.00005218442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5285115,"threshold_uncertainty_score":0.6214644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09052216572152885,"score_gpt":0.4521326449831077,"score_spread":0.3616104792615789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}