{"id":"W3205415979","doi":"10.1200/jco.21.00358","title":"Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Izaak Walton Killam Health Centre","funders":"National Cancer Institute","keywords":"Chemotherapy; Clinical trial; Phases of clinical research; Overall survival; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001241787,0.0006875857,0.001183271,0.0003098852,0.0002842013,0.0005012822,0.000656523,0.0007503873,0.003207192],"category_scores_gemma":[0.001189199,0.0003094026,0.0007865502,0.0003202192,0.000666995,0.0003475593,0.0002588861,0.00188487,0.0003062259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008275144,"about_ca_system_score_gemma":0.001991036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001567087,"about_ca_topic_score_gemma":0.004074654,"domain_scores_codex":[0.9996284,0.0002069765,0.00002222965,0.00005875626,0.00003440459,0.00004913381],"domain_scores_gemma":[0.9990854,0.0002488057,0.0002168519,0.00006075457,0.00005060274,0.0003375539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9094681,0.02264941,0.00545152,0.0003621531,0.0008033882,0.00007093589,0.00007539193,0.0009788831,0.008565606,0.0002060832,0.001964945,0.04940365],"study_design_scores_gemma":[0.8054484,0.1852581,0.005964196,0.00002783618,0.0002993941,0.0000584739,0.0000173756,0.0004766967,0.001137272,0.00008393255,0.001219999,0.000008460315],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943759,0.0009942976,0.0002483398,0.0002745221,0.0001000543,0.002392592,0.0006120141,0.00003079237,0.000971385],"genre_scores_gemma":[0.9895096,0.001448549,0.001991869,0.0006092433,0.0002270026,0.003415972,0.001237145,0.00001367436,0.001546971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003207192,"threshold_uncertainty_score":0.01072907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09052216572152885,"score_gpt":0.4521326449831077,"score_spread":0.3616104792615789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}