{"id":"W3205423300","doi":"10.1161/circulationaha.120.052023","title":"Long Noncoding RNA <i>MIAT</i> Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization","year":2021,"lang":"en","type":"article","venue":"Circulation","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; RIKEN; National Center for Advancing Translational Sciences; Johns Hopkins University","keywords":"Regulator; Proinflammatory cytokine; Long non-coding RNA; Phenotype; Negative regulator; Lesion; RNA; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002008059,0.0003000243,0.0002307592,0.000314024,0.0001641449,0.0003685944,0.0001468842,0.0002886686,0.002037597],"category_scores_gemma":[0.0002487437,0.0001725791,0.0001996617,0.000183773,0.0003312587,0.0001341261,0.0001543453,0.0003849581,0.0003459062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995871,"about_ca_system_score_gemma":0.0001225917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003096971,"about_ca_topic_score_gemma":0.0004155261,"domain_scores_codex":[0.999808,0.00002331518,0.0000167996,0.00009765253,0.00002176822,0.00003241588],"domain_scores_gemma":[0.99957,0.00004855929,0.000246579,0.00003140295,0.00002791548,0.00007560526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001484049,0.00007622048,0.01258214,0.00006900916,0.00004381096,0.0001706257,0.00004581962,0.00006563138,0.9832953,0.0001337168,0.0001468281,0.0018868],"study_design_scores_gemma":[0.0001291106,0.001737799,0.578673,0.00003272993,0.0003195098,0.002453186,0.0001935717,0.003133099,0.4087027,0.000463607,0.004121373,0.00004024161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957976,0.000612225,0.002051012,0.00008243351,0.00003040268,0.00001964364,0.0006062063,0.00008994659,0.0007105986],"genre_scores_gemma":[0.9974856,0.0002151485,0.0009201487,0.00007248208,0.00002732255,0.0000436378,0.0005098492,0.0000392561,0.0006864635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002037597,"threshold_uncertainty_score":0.006816387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01820694975548042,"score_gpt":0.270474899817907,"score_spread":0.2522679500624266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}