{"id":"W3205477273","doi":"10.3390/pharmaceutics13101736","title":"In Vitro Cellular and Molecular Interplay between Human Foreskin-Derived Mesenchymal Stromal/Stem Cells and the Th17 Cell Pathway","year":2021,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University Health Centre; Université de Montréal","funders":"Fonds De La Recherche Scientifique - FNRS; Arthritis Society","keywords":"Mesenchymal stem cell; Stromal cell; Foreskin; Proinflammatory cytokine; Cell biology; Cell therapy; Stem cell; Interleukin 17; Immunology; T cell; Cancer research; Biology; Context (archaeology); Population; Flow cytometry; Chemistry; Inflammation; Cell culture; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009518565,0.0003075777,0.0006024477,0.0001363363,0.0001538123,0.00009826551,0.0002081529,0.0001485468,0.0001283928],"category_scores_gemma":[0.0000403079,0.0002348419,0.0001163688,0.0002953415,0.0003865969,0.0001081112,0.0004928003,0.0008602126,0.00001773465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008410858,"about_ca_system_score_gemma":0.0001393932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000419316,"about_ca_topic_score_gemma":0.000006035003,"domain_scores_codex":[0.9972221,0.0004919866,0.0004878379,0.0005464864,0.0006085372,0.0006430705],"domain_scores_gemma":[0.9984629,0.000429955,0.0001055129,0.0004607934,0.0001329645,0.0004078971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002701149,0.00009591887,0.003523941,0.0003840893,0.00008829324,0.001359215,0.0008941195,0.000003019606,0.9917197,0.0002396089,0.0000815146,0.001340457],"study_design_scores_gemma":[0.006510999,0.00008965946,0.0003808935,0.00006581655,0.0001645447,0.00005757752,0.000534612,0.001909634,0.9822381,0.0001772854,0.007653908,0.0002169304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880647,0.004799283,0.0002365975,0.001472161,0.0001123055,0.0008471482,0.00003289713,0.00002861721,0.004406272],"genre_scores_gemma":[0.9968999,0.0004776082,0.0004307381,0.0005749812,0.0001260564,0.0000317069,0.00003199301,0.00005485778,0.001372147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009481568,"threshold_uncertainty_score":0.9576575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04673748368353622,"score_gpt":0.3605529118506346,"score_spread":0.3138154281670984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}