{"id":"W3205621463","doi":"10.1111/imm.13422","title":"A specialist antigen storage compartment in dendritic cells to sustain cross‐presentation","year":2021,"lang":"en","type":"letter","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Immune system; Immunology; Cross-presentation; Acquired immune system; Antigen presentation; Dendritic cell; Biology; Antigen; Antigen-presenting cell; Immunogenicity; Lymphatic system; Autoimmunity; Follicular dendritic cells; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002564823,0.0003431693,0.0004543478,0.0003198732,0.0004964245,0.001203226,0.0004641653,0.00102915,0.006533469],"category_scores_gemma":[0.0002362973,0.0001871416,0.0004208531,0.0003246912,0.0002876612,0.001035188,0.0007468573,0.0009028965,0.005702354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005733494,"about_ca_system_score_gemma":0.0004119323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001753429,"about_ca_topic_score_gemma":0.000214983,"domain_scores_codex":[0.9997947,0.00002522751,0.00001527175,0.0000572554,0.00004571233,0.00006184925],"domain_scores_gemma":[0.9998738,0.00001454796,0.0000189478,0.00002352371,0.00002918892,0.00003996472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009627971,0.00004628927,0.0004537874,0.0004637178,0.00001122483,0.0004284417,0.0001053556,0.0003512749,0.9731836,0.006085362,0.001237348,0.01753728],"study_design_scores_gemma":[0.00006713416,0.0005810274,0.004475944,0.0001994862,0.00006849765,0.004838064,0.0003313466,0.004463642,0.7932731,0.007119332,0.1845365,0.00004592723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7669084,0.05021355,0.1251201,0.003143655,0.002146764,0.000528316,0.002224735,0.002249305,0.04746514],"genre_scores_gemma":[0.9551718,0.00783503,0.01975789,0.001178922,0.0003073291,0.0002009457,0.001154252,0.0002088751,0.01418503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006533469,"threshold_uncertainty_score":0.02185667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01805765086941045,"score_gpt":0.2855374341186132,"score_spread":0.2674797832492027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}